Oprozomib
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Catalog number2386-5
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PricePlease ask
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Size5 mg
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Alternative_nameN-((S)-3-methoxy-1-(((S)-3-methoxy-1-(((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)-2-methylthiazole-5-carboxamide; ONX-0912; PR-047
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DescriptionOprozomib is a next generation, irreversible and selective proteasome inhibitor that displays potent anti-myeloma properties. It potently induces apoptosis in HNSCC cell lines via upregulation of pro-apoptotic Bik.
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CAS Number935888-69-0
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₅H₃₂N₄O₇S
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Molecular Weight532.61
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~100 mg/ml)
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HandlingProtect from light and moisture
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Tag LineA next generation proteasome inhibitor
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Storage Condition-20 ̊C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID25067547
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SMILESCC1=NC=C(S1)C(=O)NC(COC)C(=O)NC(COC)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(CO3)C
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InChiInChI=1S/C25H32N4O7S/c1-15-26-11-20(37-15)24(33)29-19(13-35-4)23(32)28-18(12-34-3)22(31)27-17(21(30)25(2)14-36-25)10-16-8-6-5-7-9-16/h5-9,11,17-19H,10,12-14H2,1-4H3,(H,27,31)(H,28,32)(H,29,33)/t17-,18-,19-,25+/m0/s1
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InChi KeySWZXEVABPLUDIO-WSZYKNRRSA-N
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MSDS AvailableYes
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Gene target
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Short nameOprozomib
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Alternative nameOprozomib
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