Oprozomib

  • Catalog number
    2386-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    N-((S)-3-methoxy-1-(((S)-3-methoxy-1-(((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)-2-methylthiazole-5-carboxamide; ONX-0912; PR-047
  • Description
    Oprozomib is a next generation, irreversible and selective proteasome inhibitor that displays potent anti-myeloma properties. It potently induces apoptosis in HNSCC cell lines via upregulation of pro-apoptotic Bik.
  • CAS Number
    935888-69-0
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₅H₃₂N₄O₇S
  • Molecular Weight
    532.61
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~100 mg/ml)
  • Handling
    Protect from light and moisture
  • Tag Line
    A next generation proteasome inhibitor
  • Storage Condition
    -20 ̊C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    25067547
  • SMILES
    CC1=NC=C(S1)C(=O)NC(COC)C(=O)NC(COC)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(CO3)C
  • InChi
    InChI=1S/C25H32N4O7S/c1-15-26-11-20(37-15)24(33)29-19(13-35-4)23(32)28-18(12-34-3)22(31)27-17(21(30)25(2)14-36-25)10-16-8-6-5-7-9-16/h5-9,11,17-19H,10,12-14H2,1-4H3,(H,27,31)(H,28,32)(H,29,33)/t17-,18-,19-,25+/m0/s1
  • InChi Key
    SWZXEVABPLUDIO-WSZYKNRRSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Oprozomib
  • Alternative name
    Oprozomib
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