-
Synonyms
Transferrin, Siderophilin, TF, DKFZp781D0156, PRO1557, PRO2086
-
Alternative_names
Transferrin, Siderophilin, TF, DKFZp781D0156, PRO1557, PRO2086
-
Description
The specific iron-binding protein in plasma.
-
Recombinant
No
-
Source
Rat Plasma
-
Purity by SDS PAGE
≥98%
-
Assay
SDS-PAGE
-
Molecular Weight
80.0 kDa
-
Storage Temp
-20°C
-
Shipping
Gel Pack
-
Shelf Life
12 months
-
Appearance
Lyophilized
-
Physical form description
Lyophilized from 20 mM Na phosphate, pH 7.4 and 150 mM NaCI.
-
Background Information
Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and in prevention of iron loss via the kidney. Stored in bone marrow as TF-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypo-proteinemias and nephritic syndrome; increases are found in pregnancy, iron-deficiency anemias and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important factor used in defined culture media.
-
Handling
Centrifuge the vial prior to opening.
-
Usage
For Research Use Only! Not to be used in humans
-
-
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
-
Latin name
Rattus norvegicus
