anti-GDF6 Antibody
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Catalog number4691
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoGDF6 Antibody: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.
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Gene namesGDF6 Antibody: KFM, KFS, KFS1, KFSL, SGM1, BMP13, CDMP2, LCA17, MCOP4, SCDO4, MCOPCB6, GDF16GDF-6
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Antibodie s labelunlabelled serum
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PurityGDF6 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenGDF6 antibody was made against a 17 amino acid synthetic peptide near the carboxy terminus of the human GDF6.
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Immuno applicationELISA, Western Blot
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Antibody adviceGDF6 antibody can be used for detection of GDF6 by Western blot at 0.5 to 1 ug/mL.
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Suspention pH azideGDF6 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atGDF6 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr48475062
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Ncbi nrNP_001001557
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr392255
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GENE symbolGDF6
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Antigene namegrowth differentiation factor 6
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SourceHomo sapiens
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Protein nrQ6KF10
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolGDF6
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Short nameanti-GDF6 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toGDF6 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetgrowth differentiation factor 6, GDF6 and IDBG-29375 and ENSG00000156466 and 392255, protein homodimerization activity, Extracellular, Gdf6 and IDBG-129105 and ENSMUSG00000051279 and 242316, BT.29849 and IDBG-645217 and ENSBTAG00000007687 and 407175
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Gene info
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Identity
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Gene
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Long gene namegrowth differentiation factor 6
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Synonyms gene
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Synonyms gene name
- segmentation syndrome 1
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Synonyms
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Locus
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Discovery year1999-04-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Transforming growth factor beta superfamily
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data