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A Disintegrin And Metalloproteinase With Thrombospondin 1 ADAMTS1 Polyclonal Antibody

A Disintegrin And Metalloproteinase With Thrombospondin 1 ADAMTS1 Polyclonal Antibody is available 28 times from Bioma labs

CAU24946 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 100 μg | 536.8 USD

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CAU24951 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 200 μg | 759.31 USD

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CAU24947 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 50 μg | 393.42 USD

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CAU24948 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 50 μg | 373.92 USD

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CAU24952 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 200 μg | 759.31 USD

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CAU24948 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 10 μg | 193.84 USD

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CAU24952 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 100 μg | 496.65 USD

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CAU24949 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 10 μg | 193.84 USD

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CAU24946 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 50 μg | 393.42 USD

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CAU24952 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 50 μg | 364.75 USD

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CAU24950 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 50 μg | 364.75 USD

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CAU24946 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 200 μg | 823.55 USD

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CAU24948 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 200 μg | 781.11 USD

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CAU24948 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 100 μg | 510.42 USD

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CAU24950 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 100 μg | 496.65 USD

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CAU24951 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 100 μg | 496.65 USD

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CAU24949 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 100 μg | 510.42 USD

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CAU24947 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 10 μg | 200.73 USD

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CAU24951 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 10 μg | 189.26 USD

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CAU24952 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 10 μg | 189.26 USD

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CAU24950 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 10 μg | 189.26 USD

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CAU24947 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 200 μg | 823.55 USD

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CAU24950 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 200 μg | 759.31 USD

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CAU24949 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 200 μg | 781.11 USD

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CAU24946 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 10 μg | 200.73 USD

Immunogen ADAMTS1 (Thr854~Ser967)
Verified reactivity Rattus norvegicus (Rat)
1. Gene info
Identity217
Long gene name ADAM metallopeptidase with thrombospondin type 1 motif 1
Synonyms gene name
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1
GenBank acession
Locus21q21.3
Discovery year 1998-11-19
Entrez gene record9510
Pubmed identfication
Classification
  • ADAM metallopeptidases with thrombospondin type 1 motif
Havana BLAST/BLATOTTHUMG00000078688
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedcleavage of semaphorin 3C induced by ADAMTS1 promotes the migration of breast cancer cells, indicating that the co-expression of these molecules in tumors may contribute to the metastatic program
cleaved by ADAMTS1 and diffrenteially inhibited by metalloproteinase inhibitors
study showed that ADAMTS-1, -4, -5 and TIMP3 were expressed at differential levels in hepatocellular carcinoma cell lines
ADAMTS1 is an important regulatory factor of angiogenesis and tumor growth in prostate tumors, where modified ADAMTS1 expression resulted in markedly changed blood vessel morphology, possibly related to altered thrombospondin 1 levels.
IL-1beta increased ADAMTS-1 mRNA and protein levels in decidual stromal cell cultures in a concentration- and time-dependent manner.
ADAMTS1 significantly blocks VEGFR2 phosphorylation due to direct binding and sequestration of VEGF165, with consequent suppression of endothelial cell proliferation.
results provide evidence for an overexpression of ADAM-12 and a lower expression of ADAMTS-1 in non-small-cell lung cancer suggest that these proteases play different functions in cancer progression
These data suggest the involvement of HDAC6 and SP1 in the HDACi-induced expression of angiostatic ADAMTS1.
disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS1) and matrix metalloproteinase-1 (MMP1), orchestrate a paracrine signaling cascade to modulate the bone microenvironment in favor of osteoclastogenesis and bone metastasis
ADAMTS1 protein levels in semen were significantly lower in males with infertility. Sperm count and motility showed a negative correlation with levels of ADAMTS1 protein expression.
Gene ontology - Cellular componentcytosol
cytoplasmic vesicle
basement membrane
InterProMetallopeptidase, catalytic domain  (A2MP1)  (AADAC)  (ABCA12)  (ABCA3)  (ABHD14B)  (ABI1)  (ABI3)  (ABL1)  (ABLIM3)  (ABRA)  (ACPP)  (ADAMTS3)  (ADAMTS6)  (ADCY10P1)  (ADIPOQ)  (ADPGK)  (ADRA1B)  (ADSL)  (AFDN)  (AGAP11)  (AKIRIN1P1)  (AKR1A1)  (AKR1C6P)  (ALKBH8)  (AMMECR1)  (AMMECR1-IT1)  (ANAPC10)  (ANKLE1)  (ANKRD19P)  (ANKRD27)  (ANO10)  (ANO2)  (ANO4)  (ANO7L1)  (ANO8)  (ANO9)  (AP1M2)  (AP1S3)  (AP2M1)  (AP4B1)  (AP4E1)  (APOL1)  (ARCN1)  (ARHGAP26)  (ARHGAP27)  (ARHGAP33)  (ARHGEF11)  (ARL6IP6)  (ARMC6)  (ARMH3)  (ARPC1B)  (ARPC3P1)  (ARPC5)  (ARPC5L)  (ARR3)  (ASAP1-IT1)  (ASAP1-IT2)  (ASAP2)  (ASPH)  (ASTN1)  (ATAD3A)  (ATF7)  (ATF7IP)  (ATG4C)  (ATP5MC3)  (ATP5ME)  (ATP5S)  (ATPAF1)  (ATXN7L3B)  (AVIL)  (B3GAT2)  (B4GALT2)  (B9D1)  (BABAM2)  (BACH2)  (BCL2L1)  (BCL6)  (BCL7A)  (BEND3)  (BEST4)  (BFAR)  (BGLT3)  (BNIP2)  (BPI)  (BRCA1P1)  (BRD7)  (BRE-AS1)  (BRI3)  (BRI3BPP1)  (BRINP1)  (BRIP1)  (BSDC1)  (BTBD18)  (BTBD9)  (BUD13)  (C2)  (CA8)  (CABS1)  (CACHD1)  (CALD1)  (CAMKK2)  (CAMLG)  (CAMSAP1)  (CAP1)  (CAPN12)  (CAPRIN2)  (CARS)  (CASC1)  (CAV2)  (CBS)  (CBX1)  (CBY3)  (CCAR1)  (CCDC171)  (CCDC34)  (CCDC73)  (CCHCR1)  (CCNG1)  (CCNI)  (CCNJL)  (CCNJP1)  (CCNYL1)  (CD2)  (CD209)  (CD2AP)  (CD80)  (CDH23)  (CDH26)  (CDH4)  (CDK5)  (CDKN3)  (CDR2)  (CELF1)  (CELF3)  (CENPA)  (CENPK)  (CENPM)  (CENPO)  (CENPP)  (CENPUP1)  (CENPX)  (CEP170)  (CEP250)  (CEP350)  (CEP55)  (CEP57)  (CEP83)  (CEPT1)  (CFAP45)  (CFAP73)  (CHCHD3)  (CHD8)  (CHRAC1)  (CHST14)  (CIAPIN1)  (CISD2)  (CISH)  (CKAP4)  (CKAP5)  (CLASRP)  (CLBA1)  (CLCA3P)  (CLCN3P1)  (CLCN5)  (CLDN14)  (CLDN16)  (CLDN6)  (CLDN8)  (CLECL1)  (CLINT1)  (CLIP1)  (CLN5)  (CLNK)  (CLRN2)  (CLSPN)  (CLSTN3)  (CLVS1)  (CLVS2)  (CMT1A)  (CNBD1)  (CNKSR2)  (CNNM3)  (CNOT2)  (CNOT3)  (CNOT4)  (CNOT6)  (CNOT6LP1)  (CNOT7)  (CNTD1)  (CNTNAP3P5)  (COLEC10)  (COMMD2)  (COPG1)  (COPS8)  (COQ8A)  (COX16)  (COX6B1P1)  (COX7A2P2)  (COX7CP1)  (CPEB4)  (CPNE3)  (CPT1A)  (CRYBA4)  (CRYBG3)  (CSDC2)  (CSF1)  (CSF2)  (CSGALNACT1)  (CSN1S2AP)  (CSRNP3)  (CST2)  (CTAG1B)  (CTHRC1P1)  (CTPS2)  (CTR9)  (CTSG)  (CTXN1)  (CUL7)  (CUX1)  (CYB561D1)  (CYFIP1)  (CYLC2)  (CYP2A13)  (CYP2B7P)  (CYP2D7)  (CYP2E1)  (CYP3A54P)  (CYP3A7)  (DAB2)  (DAD1P1)  (DALRD3)  (DAP3P2)  (DBI)  (DCDC2C)  (DDX39B)  (DEFB4B)  (DENND2D)  (DFNY1)  (DGAT2)  (DHRS7)  (DNAL4)  (DRC7)  (DSCAM-AS1)  (DSTN)  (DUSP14)  (DYM)  (DYNLL1)  (EEF2)  (EEPD1)  (EFHD2)  (EFNB1)  (EGF)  (EGFL6)  (EIF1)  (EIF3K)  (ELK3)  (ELMO1)  (ELMOD1)  (ENAM)  (EPB41L2)  (EPB41L4B)  (EPB41L5)  (ERG)  (ERV3-1)  (ERVK-19)  (FA2H)  (FABP6)  (FAM120B)  (FANCD2)  (FBXO3)  (FBXW12)  (FCP1)  (FDXR)  (FGF17)  (FGF5)  (FGFR1)  (FHAD1)  (FMR1-IT1)  (FNDC3A)  (FRMD4A)  (FRMPD2B)  (FSD1L)  (FSD2)  (FUNDC2P1)  (FXYD7)  (FYTTD1)  (GAD1)  (GAL3ST1)  (GALM)  (GAPDH)  (GEMIN8P4)  (GFOD1)  (GLB1L3)  (GLYAT)  (GOLGA6A)  (GPATCH1)  (GPKOW)  (GRIK1)  (GSDMA)  (GSTCD)  (GZMH)  (HACD1)  (HACD2)  (HAGH)  (HAP1)  (HDAC5)  (HDHD5)  (HEBP2)  (HIST1H2AE)  (HIST2H2BE)  (HLA-DOA)  (HMG20A)  (HMGA1P8)  (HMSD)  (HNRNPUL1)  (HOPX)  (HORMAD1)  (HPS5)  (HSPB6)  (HTR6)  (HYKK)  (IBSP)  (IFIH1)  (IFITM1)  (IFT74)  (IGHV3-71)  (IGKV1-12)  (IGKV2-23)  (IL1A)  (ILDR1)  (INF2)  (IQSEC1)  (ISYNA1)  (IVNS1ABP)  (JUND)  (KCNAB1-AS2)  (KCNH1)  (KCNMB2)  (KRT32)  (KTN1)  (LACTBL1)  (LEP)  (LGALS13)  (LGI3)  (LGI4)  (LIMS3)  (LIPN)  (LMLN)  (LRCH4)  (LRP12)  (MACO1)  (MACROD1)  (MADD)  (MAEA)  (MAML1)  (MAMSTR)  (MAP7)  (MAPK8)  (MATN1)  (MCUR1)  (MDGA2)  (MEA1)  (MED10)  (MED20)  (MED28)  (MED6)  (MFAP1)  (MFSD2A)  (MGAT3)  (MGAT4D)  (MIP)  (MITD1)  (MRPL1)  (MRPL22)  (MRPL37)  (MRPL55)  (MRPS36)  (MTMR3)  (MYH2)  (NARF)  (NCAPD2P1)  (NCAPH)  (NCAPH2)  (NCK1)  (NCOR1)  (NEO1)  (NF2)  (NFE2L1)  (NFYA)  (NMD3)  (NOXRED1)  (NPAS4)  (NPRL3)  (NR0B1)  (NRAS)  (NTF6A)  (NUTF2)  (OLAH)  (OPALIN)  (OR10AD1)  (OXER1)  (P4HA1)  (PAFAH1B1)  (PAH)  (PALM2)  (PASD1)  (PCAT4)  (PCDH11Y)  (PCGF1)  (PDC)  (PDCD6IP)  (PDGFA)  (PDGFRA)  (PDLIM5)  (PDZK1)  (PDZK1IP1)  (PEBP1P2)  (PES1)  (PFDN2)  (PFDN4)  (PGK1)  (PIDD1)  (PIGH)  (PIGM)  (PIGT)  (PIRC108)  (PIRC15)  (PIRC52)  (PITPNC1)  (PKDCC)  (PLA2G7)  (PLEKHN1)  (PLSCR4)  (PNISR)  (PNN)  (POLR2A)  (POMC)  (POR)  (POU2F2)  (POU5F1P3)  (PPARA)  (PPP1R1B)  (PPP1R1C)  (PPP2R2B)  (PPP5D1)  (PPRC1)  (PRELID1)  (PSD)  (PSEN1)  (PSMD1)  (PSME1)  (PTBP2)  (PTCD1)  (PTK6)  (PTPRH)  (PXMP2)  (QRSL1)  (R3HDM1)  (RAPGEF6)  (RCSD1)  (RDH14)  (RELT)  (REPIN1)  (RFTN2)  (RHOT1)  (RHOT2)  (RIOK2)  (RNF113A)  (RNF19B)  (RNF20)  (RNPEPL1)  (RNU6-2)  (RNU6-8)  (RPL15P15)  (RPL17)  (RPL22)  (RPL24)  (RPL26)  (RPL28)  (RPL30)  (RPL3L)  (RPL5P21)  (RPLP0)  (RPS10)  (RPS11)  (RPS13)  (RPS15)  (RPS18)  (RPS18P13)  (RPS2)  (RPS23)  (RPS25)  (RPS26)  (RPS29)  (RPS5)  (RPS6)  (RPS9)  (RTKN2)  (RYR1)  (S100A1)  (S100A7L2)  (S12)  (SAMD14)  (SBDS)  (SCNN1D)  (SCUBE1)  (SDR9C7)  (SEC62)  (SEPT9)  (SERPINA5)  (SERTAD4)  (SET)  (SETDB1)  (SFSWAP)  (SH2D3A)  (SH3BP5)  (SH3D19)  (SKP1)  (SLC24A2)  (SLC25A1)  (SLC25A17)  (SLC2A1)  (SLC7A3)  (SMARCA4)  (SMC4)  (SMIM24)  (SNAR-C1)  (SNAR-G1)  (SNORD115-40)  (SNRPA1)  (SNRPC)  (SNTB2)  (SNTG1)  (SNTN)  (SNX14)  (SOGA1)  (SOX13)  (SOX14)  (SPAG9)  (SPHK1)  (SPSB1)  (SPZ1)  (ST3GAL6)  (ST7-AS2)  (STAB1)  (STN1)  (STRBP)  (STT3A)  (SUMO1)  (SURF4)  (SVBP)  (SYNC)  (TANK)  (TBC1D1)  (TBXT)  (TCEA2)  (TDRD3)  (TEAD1)  (TEAD3)  (TEX10)  (TFAP4)  (TIMELESS)  (TIMP1)  (TMA7)  (TMED10P1)  (TMED11P)  (TMEM121)  (TMEM121B)  (TMEM170A)  (TMEM175)  (TMEM208)  (TMEM38A)  (TMEM70)  (TMX1)  (TNF)  (TOMM6)  (TRAFD1)  (TRAM1)  (TRE-CTC1-5)  (TRIM31)  (TRIO)  (TRIT1)  (TRS-AGA2-2)  (TRUND-NNN7-1)  (TRV-CAC1-6)  (TSFM)  (TSG101)  (TSPAN11)  (TSPAN13)  (TSPEAR)  (TSTD2)  (TTC7A)  (TWF1)  (TXNIP)  (UBALD1)  (UBASH3A)  (UBE2N)  (UBLCP1)  (UBP1)  (UCN2)  (UNC5CL)  (UXT)  (VPS26C)  (VPS9D1)  (VSIG10)  (VWC2)  (WASL)  (WDFY2)  (WDR95P)  (WFIKKN2)  (WIPF1)  (WWC2)  (XK)  (YTHDF1P1)  (ZC3H11B)  (ZFAND1)  (ZFP36)  (ZMYND19)  (ZNF212)  (ZNF277)  (ZNF597)  (ZNHIT3)  (ZPLD1)  (ZRANB1)
Thrombospondin type-1 (TSP1) repeat  (SPZ1)
Peptidase M12B, ADAM/reprolysin  (ADAMTS10)  (ADAMTS6)
Peptidase M12B, propeptide
ADAM, cysteine-rich  (ADAM11)  (ADAMTS6)
Peptidase M12B, ADAM-TS  (ADAMTS10)  (ADAMTS3)  (ADAMTS6)
ADAM-TS Spacer 1  (ADAMTS10)  (ADAMTS3)  (ADAMTS6)
Peptidase M12B, ADAM-TS1  (ADAMTS1)  (ADAMTS6)

CAU24951 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 50 μg | 364.75 USD

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CAU24947 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 100 μg | 536.8 USD

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CAU24949 | A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody size: 50 μg | 373.92 USD

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Other name C3-C5; METH1
Clonality Polyclonal
Purity Affinity purified. Please contact us for more details
Estimated production time 7-11 business days
Raised in Rabbit
NCBI number Please refer to NCBI
Gene number Please refer to GenBank
Protein number Please see Uniprot
Stroage recommendation Aliquot and store at -20°C. Minimize freezing and thawing.
Notes For research use only. Not for diagnostic procedures.
Use before 1 year
Storage recommendation Aliquot and store at -20°C. Minimize freezing and thawing.
Shipping requirements Blue ice
Antibody's concentration 200μg/ml
Supplementary information Applicable secondary antibody is available. Please inquire
Verified applications WB, ICC, IHC-P, IHC-F, ELISA
Properties If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
French translation anticorps
Short name A Disintegrin Metalloproteinase With Thrombospondin 1 (ADAMTS1) Polyclonal Antibody
Technique Polyclonal, Antibody
Alternative name A Disintegrin And Metalloproteinase including Thrombospondin 1 (ADAM metallopeptidase including thrombospondin classification 1 motif, 1) polyclonal (Antibody to)
Alternative technique polyclonals
Alternative to gene target ADAM metallopeptidase with thrombospondin type 1 motif, 1, C3-C5 and METH1, ADAMTS1 and IDBG-1192 and ENSG00000154734 and 9510, zinc ion binding, Extracellular, Adamts1 and IDBG-173182 and ENSMUSG00000022893 and 11504, ADAMTS1 and IDBG-630287 and ENSBTAG00000000706 and 512171
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