PBX3 Antibody, Cy3 Conjugated

• Catalog number
  bs-12295R-Cy3
• Price
  Please ask
• Size
  0.1ml

• Long name
  PBX3 Polyclonal Antibody, Cy3 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy3
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PBX3
• Specificity
  This is a highly specific antibody against PBX3.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human PBX3
• Gene ID number
  5090
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  512,550nm/570,615nm
• Synonyms
  Homeobox protein PBX3; MGC134053; OTTHUMP00000064213; Pbx 3; Pbx3; PBX3_HUMAN; Pre B cell leukemia homeobox 3; Pre B cell leukemia transcription factor 3; Pre-B-cell leukemia transcription factor 3; RP11 336P12.1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-PBX3 can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.
• Additional conjugation
  cy3 conjugation kit
• French translation
  anticorps

• Gene target
  PBX3   Conjugated  
• Gene symbol
  PBX3, PBX3-DT
• Short name
  Anti-PBX3
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy3
• Alternative name
  Anti-PBX3 PAb Cy3
• Alternative technique
  antibodies
• Alternative to gene target
  pre-B-cell leukemia homeobox 3, PBX3 and IDBG-85327 and ENSG00000167081 and 5090, sequence-specific DNA binding, nuclei, Pbx3 and IDBG-162874 and ENSMUSG00000038718 and 18516, BT.74403 and IDBG-638772 and ENSBTAG00000013314 and 539222

Gene info

• Identity
  HGNC:8634
• Gene
  PBX3
• Long gene name
  PBX homeobox 3
• Synonyms gene name
  • pre-B-cell leukemia transcription factor 3
  • pre-B-cell leukemia homeobox 3
• Locus
  9q33.3
• Discovery year
  1990-09-10
• Entrez gene record
  5090
• Pubmed identfication
  • 1682799
• Classification
  • TALE class homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000020684

Gene info

• Identity
  HGNC:24638
• Gene
  PBX3-DT
• Long gene name
  PBX3 divergent transcript
• Locus
  9q33.3
• Discovery year
  2021-07-28
• Entrez gene record
  51145
• RefSeq identity
  • NR_122032
• Classification
  • Divergent transcripts

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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