IGF-Binding Protein 5, Recombinant Human (IGFBP5, IBP5, IBP-5)[IGF-Binding Protein 5 Human]

• Catalog number
  MBS650382
• Price
  Please ask
• Size
  NA

• Products_type
  Recombinant Protein
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Description
  IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Binding   Protein   IGFBP5   IBP5   IBP-5   Binding   Protein  
• Gene symbol
  IGFBP5, DEF6, HTRA1, MIR1302-5, PIRC23, PIRC22, PIRC20, PIRC21, HTR6, IGHV2OR16-5
• Short name
  IGF-Binding Protein 5, Recombinant (IGFBP5, IBP5, IBP-5)[IGF-Binding Protein 5 ]
• Technique
  Recombinant, IGF, igfs, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Yeast
• Species
  Human, Humans
• Alternative name
  IGF-Binding Protein 5, Rec. H. sapiens (IGFBP5, IBP5, IBP-5)[IGF-Binding Protein 5 H. sapiens]
• Alternative technique
  rec, igfs

Gene info

• Identity
  HGNC:5474
• Gene
  IGFBP5
• Long gene name
  insulin like growth factor binding protein 5
• Synonyms gene name
  • insulin-like growth factor binding protein 5
• Locus
  2q35
• Discovery year
  1991-07-09
• Entrez gene record
  3488
• Pubmed identfication
  • 7511611
• RefSeq identity
  • NM_000599
• Classification
  • Insulin like growth factor binding proteins
• VEGA ID
  OTTHUMG00000133058

Gene info

• Identity
  HGNC:2760
• Gene
  DEF6
• Long gene name
  DEF6 guanine nucleotide exchange factor
• Synonyms gene name
  • differentially expressed in FDCP (mouse homolog) 6
  • differentially expressed in FDCP 6 homolog (mouse)
• Synonyms
  • IBP
  • SLAT
  • SWAP70L
• Synonyms name
  • SWAP-70-like adaptor protein of T cells
• GenBank acession
  • AJ276095
• Locus
  6p21.31
• Discovery year
  2000-03-29
• Entrez gene record
  50619
• Pubmed identfication
  • 19251698
• RefSeq identity
  • NM_022047
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000014563

Gene info

• Identity
  HGNC:9476
• Gene
  HTRA1
• Long gene name
  HtrA serine peptidase 1
• Synonyms gene
  • PRSS11
• Synonyms gene name
  • protease, serine, 11 (IGF binding)
• Synonyms
  • HtrA
  • IGFBP5-protease
  • ARMD7
• GenBank acession
  • AF097709
• Locus
  10q26.13
• Discovery year
  1997-07-25
• Entrez gene record
  5654
• Pubmed identfication
  • 8977104
• RefSeq identity
  • NM_002775
• Classification
  • Serine proteases
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000019186

Gene info

• Identity
  HGNC:35297
• Gene
  MIR1302-5
• Long gene name
  microRNA 1302-5
• Synonyms gene
  • MIRN1302-5
• Synonyms
  • hsa-mir-1302-5
• Locus
  20q13.13
• Discovery year
  2008-11-03
• Entrez gene record
  100302146
• RefSeq identity
  • NR_031634
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37527
• Gene
  PIRC23
• Long gene name
  piwi-interacting RNA cluster 23
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313786
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37526
• Gene
  PIRC22
• Long gene name
  piwi-interacting RNA cluster 22
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313850
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37524
• Gene
  PIRC20
• Long gene name
  piwi-interacting RNA cluster 20
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313785
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37525
• Gene
  PIRC21
• Long gene name
  piwi-interacting RNA cluster 21
• Locus
  5
• Discovery year
  2009-11-05
• Entrez gene record
  100313916
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:5301
• Gene
  HTR6
• Long gene name
  5-hydroxytryptamine receptor 6
• Synonyms gene name
  • 5-hydroxytryptamine (serotonin) receptor 6
  • 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
• Synonyms
  • 5-HT6
  • 5-HT6R
• GenBank acession
  • L41147
• Locus
  1p36.13
• Discovery year
  1997-12-11
• Entrez gene record
  3362
• Pubmed identfication
  • 8522988
• RefSeq identity
  • NM_000871
• Classification
  • 5-hydroxytryptamine receptors, G protein-coupled
• VEGA ID
  OTTHUMG00000002713

Gene info

• Identity
  HGNC:5579
• Gene
  IGHV2OR16-5
• Long gene name
  immunoglobulin heavy variable 2/OR16-5 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 2/OR16-5
• Synonyms
  • IGHV2/OR16-5
• GenBank acession
  • L25544
• Locus
  16p11.2
• Discovery year
  2000-04-17
• Entrez gene record
  100129631
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000152881

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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