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Gene info
The TCL7L2 is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. suggested that TCL7L2 acts through regulation of proglucagon through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway. The TCL7L2 gene product is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. (2005) [PubMed 15525634] suggested that TCL7L2 acts through regulation of proglucagon (MIM 138030) through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway.
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Gene names
TCF7L2, TCF-4, TCF4
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Antibodie s label
unlabelled serum
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Purity
Antibody is purified by peptide affinity chromatography method.
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Ab raised in
Rabbit
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Type
Polyclonal
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Antigen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCF7L2.
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Immuno application
ELISA, Western Blot
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Antibody advice
TCF7L2 antibody can be used for detection of TCF7L2 by ELISA at 1:2500. TCF7L2 antibody can be used for detection of TCF7L2 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azide
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep at
For short periods of storage (days) store at 4 grades C. For longer periods of storage, store TCF7L2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works with
Human
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Omim nr
170014696
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Ncbi nr
NP_110383
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KDa
65 kDa
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Vial with antibody
Lyophilized
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Quantity per ml
1 mg/ml
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NCBI GENE nr
6934
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GENE symbol
TCF7L2
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Antigene name
transcription factor 7-like 2 (T-cell specific, HMG-box)
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Source
Homo sapiens
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Protein nr
Q6FHW4
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
TCF7L2
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Short name
anti-TCF7L2 Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody totranscription factor 7-like 2 (T-cellular specific, HMG-box) (antibody to-)
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Alternative technique
antibodies
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Alternative to gene target
transcription factor 7-like 2 (T-cell specific, HMG-box), TCF-4 and TCF4, TCF7L2 and IDBG-89861 and ENSG00000148737 and 6934, armadillo repeat domain binding, nuclei, Tcf7l2 and IDBG-177837 and ENSMUSG00000024985 and 21416, TCFL2 and IDBG-639856 and ENSBTAG00000021574 and 540481
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