A-966492
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Catalog numberB2174-25
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PricePlease ask
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Size25 mg
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Alternative_name2-[2-Fluoro-4-[(2S)-2-pyrrolidinyl]phenyl]-1H-benzimidazole-7-carboxamide
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DescriptionA-966492 is a potent PARP (poly (ADP-ribose) polymerase) inhibitor that displays potency against the PARP-1 enzyme with a K(i) of 1 nM and an EC₅₀ of 1 nM in a whole cell assay.
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CAS Number934162-61-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₈H₁₇FN₄O
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Molecular Weight324.4
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Cell PermeableYes
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Purity≥98%
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA potent PARP-1 inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID16666333
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SMILESC1CC(NC1)C2=CC(=C(C=C2)C3=NC4=C(C=CC=C4N3)C(=O)N)F
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InChiInChI=1S/C18H17FN4O/c19-13-9-10(14-5-2-8-21-14)6-7-11(13
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InChi KeyAHIVQGOUBLVTCB-AWEZNQCLSA-N
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MSDS AvailableYes
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Gene target
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Gene symbolHLA-A, IGHV5-10-1, CIDEA, RPA1, CDC37P1, OR1Q1, LINC01139, FABP4, GTF2E1
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Short nameA-966492
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Alternative nameA-966492
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Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class I, A
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C1-set domain containing
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 5-10-1
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Synonyms gene
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Synonyms gene name
- immunoglobulin heavy variable 5-A (provisional, gene/pseudogene)
- immunoglobulin heavy variable 5-A (provisional)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecell death inducing DFFA like effector a
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Synonyms gene name
- cell death-inducing DFFA-like effector a
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namereplication protein A1
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Synonyms gene name
- replication protein A1 (70kD)
- replication protein A1, 70kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-12-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nucleotide excision repair
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecell division cycle 37 pseudogene 1
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Synonyms gene name
- cell division cycle 37 homolog (S. cerevisiae) pseudogene 1
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Synonyms
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Locus
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Discovery year2009-01-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameolfactory receptor family 1 subfamily Q member 1
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Synonyms gene
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Synonyms gene name
- olfactory receptor, family 1, subfamily Q, member 1
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Synonyms
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Locus
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Discovery year1999-12-09
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Entrez gene record
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Classification
- Olfactory receptors, family 1
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelong intergenic non-protein coding RNA 1139
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Synonyms
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Synonyms name
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Locus
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Discovery year2013-12-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Long intergenic non-protein coding RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefatty acid binding protein 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-08-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fatty acid binding protein family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namegeneral transcription factor IIE subunit 1
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Synonyms gene name
- general transcription factor IIE, polypeptide 1 (alpha subunit, 56kD)
- general transcription factor IIE, polypeptide 1, alpha 56kDa
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-08-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- General transcription factor IIE complex subunits
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VEGA ID
