Anti-ROM-K (Polyclonal), ALEXA Fluor 594
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Catalog numberGENTObs-2960R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptideROM-K
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SpecificityThis antibody reacts specifically with ROM-K
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ModificationNo modification has been applied to this antibody
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Modification siteNone
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsCytoplasm
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Antigen SourceKLH conjugated synthetic peptide derived from human ROM-K/KCNJ1
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Gene ID3758
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Swiss ProtN/A
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ApplicationsFCM, IF(IHC-P)
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Applications with corresponding dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200)
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Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationPotassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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SynonymsROM K; ROM-K; inwardly rectying subfamily J member 1; ATP regulated potassium channel ROM K; ATP sensitive inward rectier potassium channel 1; ATP-regulated potassium channel ROM-K; ATP-sensitive inward rectier potassium channel 1; Inward rectier K+ channel Kir1.1; inwardly rectying K+ channel; IRK1_HUMAN; KCNJ 1; KCNJ; Kcnj1; Kir 1.1; Kir1.1; Potassium channel; Potassium channel inwardly rectying subfamily J member 1; potassium inwardly-rectying channel J1; ROMK 1; ROMK 2; ROMK; ROMK1; ROMK2.
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Also known asROM-K Polyclonal Antibody
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Other nameAnti-ROM-K Polyclonal
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Gene target
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Gene symbolROM1, H4C13, TUBA1B, RAP2A, GPC4, CPAMD8, H2BC10, RAP1B
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Short nameAnti-ROM-K
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TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameROM-K Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniquepolyclonals, antibodies
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Gene info
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Identity
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Gene
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Long gene nameretinal outer segment membrane protein 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tetraspanins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameH4 clustered histone 13
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Synonyms gene
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Synonyms gene name
- H4 histone family, member K
- histone 1, H4l
- histone cluster 1, H4l
- histone cluster 1 H4 family member l
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H4 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametubulin alpha 1b
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2007-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tubulins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAP2A, member of RAS oncogene family
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Classification
- RAS type GTPase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglypican 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-08-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Glypicans
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameC3 and PZP like alpha-2-macroglobulin domain containing 8
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-04-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C3 and PZP like, alpha-2-macroglobulin domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH2B clustered histone 10
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Synonyms gene
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Synonyms gene name
- H2B histone family, member K
- histone 1, H2bi
- histone cluster 1, H2bi
- histone cluster 1 H2B family member i
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Synonyms
-
GenBank acession
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Locus
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Discovery year1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H2B histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAP1B, member of RAS oncogene family
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Synonyms
-
Locus
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Discovery year1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAS type GTPase family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
