NFIA/NF-1 Antibody

• Catalog number
  bs-11898R
• Price
  Please ask
• Size
  0.1ml

• Long name
  NFIA/NF-1 Primary Polyclonal Antibody
• Also known as
  NFIA/NF-1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  NFIA/NF-1
• Specificity
  This is a highly specific antibody against NFIA/NF-1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NFIA/NF-1
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CCAAT binding transcription factor; CCAAT Box Binding Transcription Factor; CCAAT-box-binding transcription factor; CTF; FLJ39164; NF I/A; NF-I/A; NF1 A; NF1-A; NF1A; NFI A; NFI L; NFI-A; NFIA; NFIA_HUMAN; Nuclear Factor 1 A; Nuclear factor 1 A type; Nuclear factor 1 A-type; Nuclear factor 1/A; Nuclear Factor 1A; Nuclear Factor I A; Nuclear factor I/A; nuclear factor I/X CCAAT-binding transcription factor; ynuclear factor I/X CCAAT-binding transcription factor; Nuclear factor I/X; Nuclear Factor IA; TGGCA binding protein; TGGCA-binding protein.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NFIA/NF-1  
• Gene symbol
  NF1, NFIA-AS2, NFIA, NFE4, NFE2, NFIA-AS1, GATA1, NEFH, YBX1, NFKB1
• Short name
  Anti-NFIA/NF-1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  NFIA/NF-1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7765
• Gene
  NF1
• Long gene name
  neurofibromin 1
• Synonyms name
  • neurofibromatosis
  • von Recklinghausen disease
  • Watson disease
• Locus
  17q11.2
• Discovery year
  1986-01-01
• Entrez gene record
  4763
• Pubmed identfication
  • 1715669
• RefSeq identity
  • NM_000267
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000132871
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_214

Gene info

• Identity
  HGNC:40401
• Gene
  NFIA-AS2
• Long gene name
  NFIA antisense RNA 2
• Locus
  1p31.3
• Discovery year
  2014-05-21
• Entrez gene record
  100996570
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000008421

Gene info

• Identity
  HGNC:7784
• Gene
  NFIA
• Long gene name
  nuclear factor I A
• Synonyms gene name
  • nuclear factor I/A
• Synonyms
  • NFI-L
  • KIAA1439
• GenBank acession
  • U07809
• Locus
  1p31.3
• Discovery year
  1995-03-09
• Entrez gene record
  4774
• Pubmed identfication
  • 7590749
• RefSeq identity
  • NM_005595
• Classification
  • Nuclear factor I family
• VEGA ID
  OTTHUMG00000008618

Gene info

• Identity
  HGNC:29902
• Gene
  NFE4
• Long gene name
  nuclear factor, erythroid 4
• Synonyms
  • NF-E4
• Locus
  7q22.1
• Discovery year
  2013-08-23
• Entrez gene record
  58160
• Pubmed identfication
  • 11003662
• RefSeq identity
  • NR_166510
• VEGA ID
  OTTHUMG00000157208

Gene info

• Identity
  HGNC:7780
• Gene
  NFE2
• Long gene name
  nuclear factor, erythroid 2
• Synonyms gene name
  • nuclear factor (erythroid-derived 2), 45kD
  • nuclear factor (erythroid-derived 2), 45kDa
• Synonyms
  • NF-E2
• GenBank acession
  • BC005044
• Locus
  12q13.13
• Discovery year
  1993-11-03
• Entrez gene record
  4778
• Pubmed identfication
  • 8355703
• RefSeq identity
  • NM_006163
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000169761

Gene info

• Identity
  HGNC:40402
• Gene
  NFIA-AS1
• Long gene name
  NFIA antisense RNA 1
• Synonyms
  • RP5-833A20.1
• Locus
  1p31.3
• Discovery year
  2014-05-21
• Entrez gene record
  645030
• Pubmed identfication
  • 25265644
  • 27779670
• RefSeq identity
  • NR_104180
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000040631

Gene info

• Identity
  HGNC:4170
• Gene
  GATA1
• Long gene name
  GATA binding protein 1
• Synonyms gene
  • GF1
• Synonyms gene name
  • GATA-binding protein 1 (globin transcription factor 1)
  • globin transcription factor 1
• Synonyms
  • ERYF1
  • NFE1
  • GATA-1
  • NF-E1
• Synonyms name
  • nuclear factor, erythroid 1
• GenBank acession
  • X17254
• Locus
  Xp11.23
• Discovery year
  1990-09-10
• Entrez gene record
  2623
• Pubmed identfication
  • 1999341
• RefSeq identity
  • NM_002049
• Classification
  • GATA zinc finger domain containing
• VEGA ID
  OTTHUMG00000021504
• Locus Specific Databases
  • LRG_559

Gene info

• Identity
  HGNC:7737
• Gene
  NEFH
• Long gene name
  neurofilament heavy chain
• Synonyms gene name
  • neurofilament, heavy polypeptide 200kDa
  • neurofilament heavy polypeptide
  • neurofilament heavy
• Synonyms
  • NF-H
  • NFH
• Locus
  22q12.2
• Discovery year
  1988-08-31
• Entrez gene record
  4744
• RefSeq identity
  • NM_021076
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000151155
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:8014
• Gene
  YBX1
• Long gene name
  Y-box binding protein 1
• Synonyms gene
  • NSEP1
• Synonyms gene name
  • nuclease sensitive element binding protein 1
• Synonyms
  • YB-1
  • YB1
  • DBPB
  • NSEP-1
  • MDR-NF1
  • BP-8
  • CSDB
  • CSDA2
• GenBank acession
  • BC013838
• Locus
  1p34.2
• Discovery year
  1993-10-20
• Entrez gene record
  4904
• Pubmed identfication
  • 1891370
  • 3174636
  • 29478751
• RefSeq identity
  • NM_004559
• Classification
  • Y-box binding proteins
  • U11 small nuclear ribonucleoprotein
  • U11/U12 di-snRNP
• VEGA ID
  OTTHUMG00000007523

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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