Transforming Growth Factor beta-2, Recombinant Human (TGFB2, BSC-1 Cell Growth Inhibitor, Cetermin, Glioblastoma-derived T-cell Suppressor Factor, G-TSF, MGC116892, Polyergin, TGF-beta2, TGF-beta-2)

• Catalog number
  MBS650224
• Price
  Please ask
• Size
  5x0.005 mg

• Products_type
  Active Protein
• Products_short_name
  [Transforming Growth Factor beta-2 Human]
• Other_names
  [transforming growth factor beta 2; Transforming growth factor beta-2; transforming growth factor beta-2; G-TSF; cetermin; polyergin; TGF-beta-2; OTTHUMP00000037528; OTTHUMP00000037529; BSC-1 cell growth inhibitor; glioblastoma-derived T-cell suppressor factor; transforming growth factor, beta 2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; Polyergin]
• Other_gene_names
  [TGFB2; TGFB2; MGC116892; TGF-beta2]
• Purity
  PurifiedPurified. 98% pure by non-reduced SDS gel electrophoresis.
• Form
  Supplied as a lyophilized powder in PBS, pH 2.5.
• Storage_stability
  Lyophilized powder may be stored at -20 degree C. Reconstitute to with sterile dH2O or buffer, aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Description
  For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Transforming   Growth   Factor   beta-2   TGFB2   BSC-1   Growth   Inhibitor   Cetermin   Glioblastoma-derived   Suppressor   Factor   G-TSF   MGC116892   Polyergin   TGF-beta2   TGF-beta-2  
• Gene symbol
  TGFB2, IGHV3-71, TGFB2-AS1, TGFB2-OT1, HLA-G, NCAPG, FOLR3, SLC12A2, SNRPG, GNAO1
• Short name
  Transforming Growth Factor beta-2, Recombinant (TGFB2, BSC-1 Growth Inhibitor, Cetermin, Glioblastoma-derived T- Suppressor Factor, G-TSF, MGC116892, Polyergin, TGF-beta2, TGF-beta-2)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  bacteria
• Species
  Human, Humans
• Alternative name
  Transforming Growth Factor b-2, Rec. H. sapiens (transforming growth factor, b 2, BSC-1 cellular Growth suppressor, Cetermin, Glioblastoma-derived T-cellular Suppressor Factor, G-TSF, MGC116892, Polyergin, TGF-beta2, TGF-b-2)
• Alternative technique
  rec
• Alternative to gene target
  transforming growth factor, beta 2, LDS4 and TGF-beta2, TGFB2 and IDBG-106710 and ENSG00000092969 and 7042, protein heterodimerization activity, Extracellular, Tgfb2 and IDBG-208111 and ENSMUSG00000039239 and 21808, TGFB2 and IDBG-629908 and ENSBTAG00000005359 and 534069
• Tissue
  cell

Gene info

• Identity
  HGNC:11768
• Gene
  TGFB2
• Long gene name
  transforming growth factor beta 2
• Synonyms gene name
  • transforming growth factor, beta 2
• Synonyms name
  • prepro-transforming growth factor beta-2
• GenBank acession
  • M19154
• Locus
  1q41
• Discovery year
  1989-05-10
• Entrez gene record
  7042
• RefSeq identity
  • NM_003238
• Classification
  • Transforming growth factor beta family
• VEGA ID
  OTTHUMG00000039521

Gene info

• Identity
  HGNC:5621
• Gene
  IGHV3-71
• Long gene name
  immunoglobulin heavy variable 3-71 (pseudogene)
• Synonyms gene
  • IGHV3-G
• Synonyms gene name
  • immunoglobulin heavy variable 3-71
  • immunoglobulin heavy variable 3-G pseudogene (provisional)
  • immunoglobulin heavy variable 3-G (provisional)
  • immunoglobulin heavy variable 3-71 pseudogene
• Synonyms
  • IGHV3-g
• GenBank acession
  • AB019437
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28411
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151881

Gene info

• Identity
  HGNC:50628
• Gene
  TGFB2-AS1
• Long gene name
  TGFB2 antisense RNA 1 (head to head)
• Synonyms
  • NR_046268
• GenBank acession
  • BX099841
• Locus
  1q41
• Discovery year
  2014-05-30
• Entrez gene record
  728463
• Pubmed identfication
  • 27816668
• RefSeq identity
  • NR_046268
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000039520

Gene info

• Identity
  HGNC:50629
• Gene
  TGFB2-OT1
• Long gene name
  TGFB2 overlapping transcript 1
• Synonyms
  • FLJ11812
• GenBank acession
  • AK021874
• Locus
  1q41
• Discovery year
  2014-05-30
• Entrez gene record
  103611157
• Pubmed identfication
  • 24879147
  • 25437332
• RefSeq identity
  • NR_125715
• Classification
  • Overlapping transcripts
• VEGA ID
  OTTHUMG00000189749

Gene info

• Identity
  HGNC:4964
• Gene
  HLA-G
• Long gene name
  major histocompatibility complex, class I, G
• Synonyms gene name
  • HLA-G histocompatibility antigen, class I, G
• Synonyms name
  • b2 microglobulin
• Locus
  6p22.1
• Discovery year
  1990-09-10
• Entrez gene record
  3135
• RefSeq identity
  • NM_002127
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031157
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:24304
• Gene
  NCAPG
• Long gene name
  non-SMC condensin I complex subunit G
• Synonyms gene name
  • non-SMC condensin I complex, subunit G
• Synonyms
  • FLJ12450
  • hCAP-G
  • CAP-G
  • YCG1
• Synonyms name
  • chromosome condensation protein G
• GenBank acession
  • AF331796
• Locus
  4p15.31
• Discovery year
  2006-09-04
• Entrez gene record
  64151
• Pubmed identfication
  • 10910072
  • 11136719
• RefSeq identity
  • NM_022346
• Classification
  • Armadillo like helical domain containing
  • Condensin I subunits
• VEGA ID
  OTTHUMG00000128539

Gene info

• Identity
  HGNC:3795
• Gene
  FOLR3
• Long gene name
  folate receptor gamma
• Synonyms gene name
  • folate receptor 3 (gamma)
  • folate receptor 3
• Synonyms
  • FR-G
  • FRγ
• GenBank acession
  • U08471
• Locus
  11q13.4
• Discovery year
  1997-09-05
• Entrez gene record
  2352
• Pubmed identfication
  • 8110752
• RefSeq identity
  • NM_000804
• VEGA ID
  OTTHUMG00000167870

Gene info

• Identity
  HGNC:10911
• Gene
  SLC12A2
• Long gene name
  solute carrier family 12 member 2
• Synonyms gene name
  • solute carrier family 12 (sodium/potassium/chloride transporter), member 2
• Synonyms
  • NKCC1
  • BSC
  • BSC2
  • PPP1R141
• Synonyms name
  • bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1
  • basolateral Na-K-Cl symporter
  • protein phosphatase 1, regulatory subunit 141
• Locus
  5q23.3
• Discovery year
  1994-02-16
• Entrez gene record
  6558
• Pubmed identfication
  • 7629105
• RefSeq identity
  • NM_001046
• Classification
  • Solute carriers
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000128983

Gene info

• Identity
  HGNC:11163
• Gene
  SNRPG
• Long gene name
  small nuclear ribonucleoprotein polypeptide G
• Synonyms
  • Sm-G
• GenBank acession
  • X85373
• Locus
  2p13.3
• Discovery year
  1990-06-13
• Entrez gene record
  6637
• Pubmed identfication
  • 7744013
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000129670

Gene info

• Identity
  HGNC:4389
• Gene
  GNAO1
• Long gene name
  G protein subunit alpha o1
• Synonyms gene name
  • guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
• Synonyms
  • G-ALPHA-o
• Locus
  16q13
• Discovery year
  1988-04-24
• Entrez gene record
  2775
• Pubmed identfication
  • 1899283
  • 11395521
• RefSeq identity
  • NM_020988
• Classification
  • G protein subunits alpha, group i
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133241

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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