Rab3A Antibody

• Catalog number
  R31735
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Rab3A
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Rab3A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Rab3A antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  5864
• Purity
  Antigen affinity
• Description
  Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene. Synapsin I stimulated the Rab3A cycle by increasing GTP binding, GTPase activity, and Rab3A recruitment to the synaptic vesicle membrane. Conversely, Rab3A inhibited Synapsin I binding to actin and Synapsin I-induced synaptic vesicle clustering. It has been found that the protein is necessary for both forms of synaptic plasticity, and it is also involved in calcium exocytosis in neurons. In addition to that, Rab3A has been found to regulate a late step in synaptic vesicle fusion.
• Immunogen
  Amino acids 192-220 (DTADPAVTGAKQGPQLSDQQVPPHQDCAC-human) were used as the immunogen for this Rab3A antibody.
• Storage
  After reconstitution, the Rab3A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Rab3A  
• Gene symbol
  RAB3A, RAB3IL1, RAB3IP
• Short name
  Anti-Rab3A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Rab3A
• Alternative technique
  antibodies
• Alternative to gene target
  RAB3A, member RAS oncogene family, RAB3A and IDBG-37807 and ENSG00000105649 and 5864, ATPase binding, nuclei, Rab3a and IDBG-164008 and ENSMUSG00000031840 and 19339, RAB3A and IDBG-641746 and ENSBTAG00000010635 and 282029

Gene info

• Identity
  HGNC:9777
• Gene
  RAB3A
• Long gene name
  RAB3A, member RAS oncogene family
• Synonyms name
  • RAS-associated protein RAB3A
• Locus
  19p13.11
• Discovery year
  1989-06-30
• Entrez gene record
  5864
• Pubmed identfication
  • 2687157
  • 7532276
• RefSeq identity
  • NM_002866
• Classification
  • RAB, member RAS oncogene GTPases
• VEGA ID
  OTTHUMG00000137378

Gene info

• Identity
  HGNC:9780
• Gene
  RAB3IL1
• Long gene name
  RAB3A interacting protein like 1
• Synonyms gene name
  • RAB3A interacting protein (rabin3)-like 1
• Synonyms
  • GRAB
• Synonyms name
  • guanine nucleotide exchange factor for Rab3A
• GenBank acession
  • AF084557
• Locus
  11q12.2-q12.3
• Discovery year
  1998-07-30
• Entrez gene record
  5866
• Pubmed identfication
  • 11516400
• RefSeq identity
  • NM_013401
• VEGA ID
  OTTHUMG00000167524

Gene info

• Identity
  HGNC:16508
• Gene
  RAB3IP
• Long gene name
  RAB3A interacting protein
• Synonyms
  • RABIN3
  • FLJ22548
  • RABIN8
• Synonyms name
  • rabin3
• Locus
  12q15
• Discovery year
  2001-11-12
• Entrez gene record
  117177
• Pubmed identfication
  • 12221131
• RefSeq identity
  • NM_022456
• VEGA ID
  OTTHUMG00000169437

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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