Anti-MAGE-1 (Polyclonal), ALEXA Fluor 594
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Catalog numberGENTObs-0817R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptideMAGE-1
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SpecificityThis antibody reacts specifically with MAGE-1
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ModificationNo modification has been applied to this antibody
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Modification siteNone
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsCytoplasm
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Antigen SourceKLH conjugated synthetic peptide derived from human MAGE-1
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Gene ID4100
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Swiss ProtP43355
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ApplicationsIF(IHC-P)
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Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
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Cross reactive speciesHuman (Homo sapiens)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationMay be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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SynonymsCT1.1; MAGE1; Melanoma-associated antigen 1; Antigen MZ2-E; Cancer/testis antigen 1.1; MAGE-1 antigen; MAGEA1; MAGE1A
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Also known asMAGE-1 Polyclonal Antibody
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Other nameAnti-MAGE-1 Polyclonal
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Gene target
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Gene symbolMAGED4, MAGEA1, MAGED2, MAGEA4, MAGEB5, TRO, MAGEC2, MAGEB6, MAGEC3, MAGEB2
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Short nameAnti-MAGE-1
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TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameMAGE-1 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniquepolyclonals, antibodies
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Gene info
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Identity
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Gene
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Long gene nameMAGE family member D4
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Synonyms gene name
- melanoma antigen family D4
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-12-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAGE family
- Small nucleolar RNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMAGE family member A1
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Synonyms gene
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Synonyms gene name
- melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
- melanoma antigen family A1
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-04-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAGE family
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameMAGE family member D2
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Synonyms gene name
- melanoma antigen family D2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-08-16
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Entrez gene record
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RefSeq identity
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Classification
- MAGE family
- Small nucleolar RNA protein coding host genes
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameMAGE family member A4
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Synonyms gene
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Synonyms gene name
- melanoma antigen family A4
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-04-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAGE family
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameMAGE family member B5
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Synonyms gene name
- melanoma antigen family B5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-12-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAGE family
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nametrophinin
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-10-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAGE family
- Small nucleolar RNA protein coding host genes
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameMAGE family member C2
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Synonyms gene
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Synonyms gene name
- melanoma antigen, family E, 1, cancer/testis specific
- melanoma antigen family C2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAGE family
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameMAGE family member B6
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Synonyms gene name
- melanoma antigen family B6
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-12-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAGE family
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameMAGE family member C3
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Synonyms gene name
- melanoma antigen family C3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-12-10
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Entrez gene record
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Pubmed identfication
-
RefSeq identity
-
Classification
- MAGE family
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VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameMAGE family member B2
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Synonyms gene name
- melanoma antigen family B2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-08-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAGE family
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data