c-erbB2, p185 (HER2, neu Receptor) (Biotin)
-
Catalog number
MBS602594
-
Price
Please ask
-
Size
100 Tests
-
-
Products_type
Antibody
-
Products_short_name
[c-erbB2, p185]
-
Products_name_syn
[Anti -c-erbB2, p185 (HER2, neu Receptor) (Biotin)]
-
Clonality
Monoclonal
-
Clone
[6D12]
-
Reactivity
Human
-
Specificity
Recognizes human c-erbB-2, p185 (HER-2/neu).
-
Purity
Highly Purified Highly purified (SDS-PAGE).
-
Form
Supplied as a liquid in 50mM Tris, 100mM NaCl, 1% BSA and 0.02% sodium azide, pH 7.4. Labeled with biotin.
-
Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
-
Tested_application
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
-
Properties
Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
-
Conjugation
Biotinylated
-
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Gene target
-
Gene symbol
ERBB2
-
Short name
c-erbB2, p185 (HER2, neu Receptor) ( )
-
Host
Mouse
-
Isotype
IgG1
-
Label
Biotin
-
Alternative name
c-v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), p185 (HER2, neu Receptor) (biotinilated)
-
Alternative to gene target
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), CD340 and HER-2 and HER-2/neu and HER2 and MLN 19 and NEU and NGL and TKR1, ERBB2 and IDBG-46068 and ENSG00000141736 and 2064, transferase activity, nuclei, Erbb2 and IDBG-210591 and ENSMUSG00000062312 and 13866, ERBB2 and IDBG-639410 and ENSBTAG00000021798 and 505709
-
Gene info
Similar products
