Filters
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing

Human Recombinant HSP70 Protein

Human Recombinant HSP70 Protein is available 12 times from Stressmark proteins labs

SPR-108A | Human Recombinant HSP70 Protein size: 50 µg | 325.63 USD

Loading

SPR-103C | Human Recombinant HSP70 Protein size: 2x100 µg | 748.74 USD

Loading

SPR-115A | Human Recombinant HSP70 Protein size: 50 µg | 377.69 USD

Loading

SPR-117B | Human Recombinant HSP70 Protein size: 100 µg | 574.84 USD

Loading

SPR-117C | Human Recombinant HSP70 Protein size: 2x100 µg | 980.23 USD

Loading

SPR-115B | Human Recombinant HSP70 Protein size: 100 µg | 528.33 USD

Loading

SPR-108C | Human Recombinant HSP70 Protein size: 2x100 µg | 748.74 USD

Catalog number SPR-108C
Price 748.74 USD
Size 2x100 µg
Certificate of analysis This product has been certified >95% pure using SDS-PAGE analysis. The protein has ATPase activity at the time of manufacture of 3.0µM phosphate liberated/hr/µg protein in a 200µl reaction at 37°C (pH7.5) in the presence of 20ul of 1mM ATP using a Malachite Green assay.
Protein description Active Human Recombinant HSP70 Full Length Protein
Other name HSP70 1 Protein, HSP70 2 Protein, HSP70.1 Protein, HSP72 Protein, HSP73 Protein, HSPA1 Protein, HSPA1A Protein, HSPA1B Protein
NCBI number NM_005345
Relevant bio activity ATPase active
Protein expression model E. coli
Protein charasterics Full Length
Peptide sequence MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD
Protein purification Multi-Step Purified
Recommended buffer for storage 50mM Tris/HCl pH7.5, 2.5mM Bme, 0.15M NaCl, 10% glycerol
Protein tag No tag
Bibliography 1. Zho J. (1998) Cell. 94: 471-480. 2. Boorstein, W. R., Ziegelhoffer, T. & Craig, E. A. (1993) J. Mol. Evol. 38(1): 1-17. 3. Rothman J. (1989) Cell. 59: 591 -601. 4. DeLuca-Flaherty et al. (1990) Cell. 62: 875-887. 5. Bork P., Sander C. & Valencia A. (1992) Proc. Natl Acad. Sci. USA. 89: 7290-7294. 6. Fink A.L. (1999) Physiol. Rev. 79: 425-449. 7. Smith D.F., et al., (1993) Mol. Cell. Biol. 13(2): 869-876. 8. Prapapanich V., et al., (1996) Mol. Cell. Biol. 16(11): 6200-6207. 9. Fernandez-Funez et al., (2000) Nature. 408(6808): 101-106.
Release date 1-Oct-2007
PubMed number Not added. Please refer to PubMed
Tested applications to be tested
Tested species reactivity to be tested
Representative figure legend SDS-PAGE of 70kDa Hsp70 protein (SPR-108). SDS-Page of human HSP70 Protein (SPR-108)
Net weight (g) 0.2
1. Gene info
Identity5233
GeneHSPA1B
Synonyms gene name
  • heat shock 70kD protein 1B
  • heat shock 70kDa protein 1B
Synonyms
Locus6p21.33
Discovery year1995-08-11
Pubmed identfication
Havana BLAST/BLATOTTHUMG00000031202
2. Gene info
Identity38788
Synonyms gene name
  • suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 13
Discovery year2010-08-11
RefSeq identity
Havana BLAST/BLATOTTHUMG00000018979
MeSH Data
Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
Product images
    #Human#.jpg

SPR-103A | Human Recombinant HSP70 Protein size: 50 µg | 325.63 USD

Loading

SPR-103B | Human Recombinant HSP70 Protein size: 100 µg | 426.43 USD

Loading

SPR-108B | Human Recombinant HSP70 Protein size: 100 µg | 426.43 USD

Loading

SPR-117A | Human Recombinant HSP70 Protein size: 50 µg | 402.06 USD

Loading

SPR-115C | Human Recombinant HSP70 Protein size: 2x100 µg | 913.77 USD

Loading
Stock availability In Stock
Scientific context HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 50% identity (2). The N-terminal two thirds of HSP70s are more conserved than the C-terminal third. HSP70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides (3). When HSC70 (constitutively expressed) present in mammalian cells was truncated, ATP binding activity was found to reside in an N-terminal fragment of 44kDa which lacked peptide binding capacity. Polypeptide binding ability therefore resided within the C-terminal half (4). The structure of this ATP binding domain displays multiple features of nucleotide binding proteins (5). All HSP70s, regardless of location, bind proteins, particularly unfolded ones. The molecular chaperones of the HSP70 family recognize and bind to nascent polypeptide chains as well as partially folded intermediates of proteins preventing their aggregation and misfolding. The binding of ATP triggers a critical conformational change leading to the release of the bound substrate protein (6). The universal ability of HSP70s to undergo cycles of binding to and release from hydrophobic stretches of partially unfolded proteins determines their role in a great variety of vital intracellular functions such as protein synthesis, protein folding and oligomerization and protein transport. Looking for more information on HSP70? Visit our new HSP70 Scientific Resource Guide at more.
Protein target HSP70
Protein reactivity Human
Primary research area Cancer, Heat Shock
Category Protein
Brand name none
Origin Recombinant
Gene number 3303
Protein number P08107
Verified applications WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA
Purity pourcentage >90% High purity
Protein concentration Lot/batch specific. See included datasheet.
Protein specificity ~70 kDa
Storage recommendations -20°C
Shipping recommendations Blue Ice or 4°C
Supplementary useful information Please see included datasheet or contact us
Protein cell localization Cytoplasm
Warnings Non-hazardous materials
Protein origin Canada
Total weight (kg) 1.4
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source Recombinants or rec. proteins
Group recombinants
Gene targetHSP70 Protein
Short name Recombinant HSP70 Protein
Technique Recombinant
Species Human
Alternative name H. sapiens recombinant HSP70 Protein
Alternative technique rec
Similar products
No similar products groups has been found
Ask
Ajax processing
Close
Human Recombinant HSP70 Protein cat.: SPR-108C - Gentaur.com
Filters
+32-(0)1-658-90-45 [email protected]
  • HSP70
  • Protein
Back
Contact us
Ajax processing
Close
Chat with gentaur.com employee