Rabbit anti-human TFIIH basal transcription factor complex helicase XPD subunit polyclonal Antibody(ERCC2)

• Catalog number
  MBS1495677
• Price
  Please ask
• Size
  0,05 mL

• Other size
  please contact us to order other different size
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Test
  MyBioSource supplies antibodies that are for research of human proteins.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  TFIIH   basal   transcription   factor   complex   helicase   XPD   subunit   ERCC2  
• Gene symbol
  ERCC2, GTF2H4, GTF2H1, GTF2H3, GTF2H2, GTF2H5
• Short name
  Rabbit anti- TFIIH basal transcription factor complex helicase XPD subunit polyclonal Antibody(ERCC2)
• Technique
  anti-Human, Polyclonal, Antibody, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  production species: rabbit Antibody tohuman TFIIH basal transcription factor aggregate helicase XPD functionnal sequence polyclonal (antibody to-)(excision repair cross-complementing rodent repair deficiency, complementation family 2)
• Alternative technique
  polyclonals, antibodies, rabbit-anti
• Alternative to gene target
  excision repair cross-complementing rodent repair deficiency, complementation group 2, COFS2 and EM9 and TFIIH and TTD and XPD, ERCC2 and IDBG-57385 and ENSG00000104884 and 2068, hydrolase activity, nuclei, Ercc2 and IDBG-150400 and ENSMUSG00000030400 and 13871, ERCC2 and IDBG-639452 and ENSBTAG00000002072 and 100125238

Gene info

• Identity
  HGNC:3434
• Gene
  ERCC2
• Long gene name
  ERCC excision repair 2, TFIIH core complex helicase subunit
• Synonyms gene
  • XPD
• Synonyms gene name
  • xeroderma pigmentosum complementary group D
  • excision repair cross-complementing rodent repair deficiency, complementation group 2
  • excision repair cross-complementation group 2
• Synonyms
  • MAG
  • EM9
  • MGC102762
  • MGC126218
  • MGC126219
• Synonyms name
  • excision repair cross-complementing rodent repair deficiency, complementation group 2 protein
  • TFIIH basal transcription factor complex helicase XPB subunit
• Locus
  19q13.32
• Discovery year
  2001-06-22
• Entrez gene record
  2068
• Pubmed identfication
  • 8413672
  • 2184031
• RefSeq identity
  • NM_000400
• Classification
  • Xeroderma pigmentosum complementation groups
  • ERCC excision repair associated
  • DNA helicases
  • General transcription factor IIH complex subunits
• VEGA ID
  OTTHUMG00000048190
• Locus Specific Databases
  • The Globin Gene Server
  • LRG_461

Gene info

• Identity
  HGNC:4658
• Gene
  GTF2H4
• Long gene name
  general transcription factor IIH subunit 4
• Synonyms gene name
  • general transcription factor IIH, polypeptide 4 (52kD subunit)
  • general transcription factor IIH, polypeptide 4, 52kDa
• Synonyms
  • TFB2
  • TFIIH
  • P52
• GenBank acession
  • Y07595
• Locus
  6p21.33
• Discovery year
  1998-08-19
• Entrez gene record
  2968
• Pubmed identfication
  • 9118947
• RefSeq identity
  • NM_001517
• Classification
  • Nucleotide excision repair
  • General transcription factor IIH complex subunits
• VEGA ID
  OTTHUMG00000031043

Gene info

• Identity
  HGNC:4655
• Gene
  GTF2H1
• Long gene name
  general transcription factor IIH subunit 1
• Synonyms gene name
  • general transcription factor IIH, polypeptide 1 (62kD subunit)
  • general transcription factor IIH, polypeptide 1, 62kDa
• Synonyms
  • BTF2
  • P62
  • TFIIH
• Locus
  11p15.1
• Discovery year
  1993-08-16
• Entrez gene record
  2965
• Pubmed identfication
  • 1529339
  • 8162052
• RefSeq identity
  • NM_005316
• Classification
  • General transcription factor IIH complex subunits
  • Nucleotide excision repair
• VEGA ID
  OTTHUMG00000167690

Gene info

• Identity
  HGNC:4657
• Gene
  GTF2H3
• Long gene name
  general transcription factor IIH subunit 3
• Synonyms gene name
  • general transcription factor IIH, polypeptide 3 (34kD subunit)
  • general transcription factor IIH, polypeptide 3, 34kDa
• Synonyms
  • BTF2
  • TFIIH
  • P34
• GenBank acession
  • Z30093
• Locus
  12q24.31
• Discovery year
  1994-11-01
• Entrez gene record
  2967
• Pubmed identfication
  • 8194529
• RefSeq identity
  • NM_001516
• Classification
  • General transcription factor IIH complex subunits
  • Nucleotide excision repair
• VEGA ID
  OTTHUMG00000168697

Gene info

• Identity
  HGNC:4656
• Gene
  GTF2H2
• Long gene name
  general transcription factor IIH subunit 2
• Synonyms gene name
  • general transcription factor IIH, polypeptide 2 (44kD subunit)
  • general transcription factor IIH, polypeptide 2, 44kDa
• Synonyms
  • BTF2
  • TFIIH
  • BTF2P44
  • T-BTF2P44
  • p44
• GenBank acession
  • Z30094
• Locus
  5q13.2
• Discovery year
  1994-11-01
• Entrez gene record
  2966
• Pubmed identfication
  • 8194529
• RefSeq identity
  • NM_001515
• Classification
  • Nucleotide excision repair
  • General transcription factor IIH complex subunits
• VEGA ID
  OTTHUMG00000164542

Gene info

• Identity
  HGNC:21157
• Gene
  GTF2H5
• Long gene name
  general transcription factor IIH subunit 5
• Synonyms gene
  • C6orf175
  • TTD
• Synonyms gene name
  • chromosome 6 open reading frame 175
  • trichothiodystrophy
  • general transcription factor IIH, polypeptide 5
• Synonyms
  • FLJ30544
  • bA120J8.2
  • TTD-A
  • TFB5
  • TFIIH
  • TTDA
• Synonyms name
  • DNA repair syndrome trichothiodystrophy group A
• GenBank acession
  • AK055106
• Locus
  6q25.3
• Discovery year
  2003-11-25
• Entrez gene record
  404672
• Pubmed identfication
  • 15220921
• RefSeq identity
  • NM_207118
• Classification
  • General transcription factor IIH complex subunits
  • Nucleotide excision repair
• VEGA ID
  OTTHUMG00000015906
• Locus Specific Databases
  • LRG_469

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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