FANCD2 (Ser222) Antibody

• Catalog number
  bs-3015R
• Price
  Please ask
• Size
  0.1ml

• Long name
  FANCD2 (Ser222) Primary Polyclonal Antibody
• Also known as
  FANCD2 (Ser222) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  FANCD2 Ser222
• Specificity
  This is a highly specific antibody against FANCD2 Ser222.
• Modification s
  Phosphorylation
• Modification site s
  Ser222
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human FANCD2 around the phosphorylation site of Ser222
• Gene ID number
  2177
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  FANCD2 phospho S222; FANCD2 phospho Ser222; p-FANCD2 phospho S222; FA 4; FA D2; FA4; FAC D2; FACD 2; FACD; FACD2; FAD; FAD2; FANC D2; FANCD 2; FANCD; Protein FACD2; Type 4 Fanconi pancytopenia; FACD2_HUMAN; Fanconi anemia group D2 protein; Protein FACD2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FANCD2   Ser222  
• Gene symbol
  FANCD2
• Short name
  Anti-FANCD2 Ser222
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  FANCD2 (Ser222) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  Fanconi anemia, complementation group D2, FA-D2 and FA4 and FACD and FAD and FAD2 and FANCD, FANCD2 and IDBG-17539 and ENSG00000144554 and 2177, DNA polymerase binding, nuclei, Fancd2 and IDBG-177677 and ENSMUSG00000034023 and 211651, FANCD2 and IDBG-644629 and ENSBTAG00000010077 and 515845

Gene info

• Identity
  HGNC:3585
• Gene
  FANCD2
• Long gene name
  FA complementation group D2
• Synonyms gene
  • FACD
  • FANCD
• Synonyms gene name
  • Fanconi anemia complementation group D2
• Synonyms
  • FAD
  • FA-D2
• GenBank acession
  • AF340183
• Locus
  3p25.3
• Discovery year
  1996-01-04
• Entrez gene record
  2177
• Pubmed identfication
  • 7581463
  • 11239453
  • 18475298
• Classification
  • FA complementation groups
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000128670
• Locus Specific Databases
  • Fanconi Anaemia Mutation Database
  • Global Variome shared LOVD
  • LRG_306

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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