Other name 5-[1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid
Supplied with N/A
Description Cell-permeable. A potent and ATP-competitive inhibitor of PDGF, VEGF and FGF receptor tyrosine kinases (RTKs) with IC₅₀ values of 0.06, 2.43, 3.04 and> 100 μM at PDGFRβ, VEGFR2, FGFR1 and EGFR respectively. Acts as a potent antiangiogenic and antitumor agent.
Molecular formula C₁₈H₁₈N₂O₃
Is it cell-permeable? Yes
Molecular weight 310.35
Storage condition -20°C
Shipping condition gel pack
Peptide sequence N/A
Is this a salt? No
CAS number 252916-29-3
Storage instructions Protect from light
Maximum time for storage 36 months
Physical appearance Orange red solid
Reconstitute instructions DMSO (~100 mM)
Additional description For cells, cell lines and tissues in culture till half confluency.