KS-176

Alternative_name

N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide
Description

KS-176 is a potent and specific inhibitor of Breast Cancer Resistance Protein (BCRP) / ATP-binding cassette sub-family G member 2 (ABCG2). Displays no inhibitory activity against P-gp or MRP1.
CAS Number

1253452-78-6
Structure Available

Yes
Salt Form

No
Molecular Formula

C₂₂H₁₉N₃O₅
Molecular Weight

405.4
Cell Permeable

Yes
Purity

≥98% by HPLC
Solubilities

DMSO (>35 mg/ml)
Handling

Protect from air and light
Tag Line

A potent and specific inhibitor of Breast Cancer Resistance Protein (BCRP) / ATP-binding cassette sub-family G member 2 (ABCG2).
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

36 months
MDL Number

MFCD22666402
PubChem CID

49779726
PubChem CID Link
SMILES

C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)CCO)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-]
InChi

InChI=1S/C22H19N3O5/c26-14-13-15-5-9-17(10-6-15)23-22(28)19-3-1-2-4-20(19)24-21(27)16-7-11-18(12-8-16)25(29)30/h1-12,26H,13-14H2,(H,23,28)(H,24,27)
InChi Key

LTWQQWSXYYXVGA-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes