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Gene info
SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and is a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in its gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease.
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Gene names
SLC11A1, LSH, NRAMP, NRAMP1
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Antibodie s label
unlabelled serum
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Purity
Antibody is purified by protein A chromatography method.
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Ab raised in
Rabbit
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Type
Polyclonal
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Antigen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC11A1.
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Immuno application
ELISA, Western Blot
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Antibody advice
SLC11A1 antibody can be used for detection of SLC11A1 by ELISA at 1:1562500. SLC11A1 antibody can be used for detection of SLC11A1 by western blot at 1.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azide
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep at
For short periods of storage (days) store at 4 grades C. For longer periods of storage, store SLC11A1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works with
Human, Rat
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Omim nr
109255241
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Ncbi nr
NP_000569
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KDa
61 kDa
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Vial with antibody
Lyophilized
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Quantity per ml
1 mg/ml
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NCBI GENE nr
6556
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GENE symbol
SLC11A1
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Antigene name
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
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Source
Homo sapiens
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Protein nr
P49279
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
SLC11A1
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Short name
anti-SLC11A1 Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody tosolute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (antibody to-)
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Alternative technique
antibodies
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Alternative to gene target
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1, LSH and NRAMP and NRAMP1, SLC11A1 and IDBG-80969 and ENSG00000018280 and 6556, proton antiporter activity, Plasma membranes, Slc11a1 and IDBG-166877 and ENSMUSG00000026177 and 18173, SLC11A1 and IDBG-643814 and ENSBTAG00000015520 and 282470
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