RBBP4 Antibody
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Catalog number6154-100
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PricePlease ask
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Size100 μg
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Antibody TargetRBBP4
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Target Alternative NameNURF55, RBAP48
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat
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Immunogen SequenceRecombinant protein of human RBBP4
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AccessionQ09028
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Gene Id5928
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AppearanceColorless liquid
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FormLiquid
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Concentration1 mg/ml
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Formulation100 µg of antibody in 100 µl PBS containing 0.02% sodium azide, 50% glycerol, pH 7.3
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PurificationAffinity purified
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ApplicationWestern blot, Immunohistochemistry
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Positive ControlWestern Blot: Various cell lysates
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Application And UsagesWestern blot: 1:500 – 1:2000, IHC: 1:50 – 1:200.
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DescriptionRetinoblastoma associated proteins 46 and 48 (RBAP46 and RBAP48; also known as RBBP7 and RBBP4) were first characterized in human cells as proteins that bind to the retinoblastoma (Rb) tumor suppressor protein. Since then, these proteins have been shown to be components of many protein complexes involved in chromatin regulation, including the chromatin assembly factor 1 (CAF1) complex and type B histone acetyltransferase complex HAT1, both of which function in chromatin assembly during DNA replication. RBAP46 and RBAP48 are also found in the nucleosome remodeling factor complex NURF, the nucleosome remodeling and histone deacetylation complex NuRD, and the Sin3/HDAC histone deacetylation complex. More recently, RBAP46 and RBAP48 were identified as components of the polycomb repressor complex PRC2, which also contains EED and Ezh2. RBAP46 and RBAP48 bind to the histone fold region of histone H4 and are believed to target these chromatin remodeling, histone acetylation, and histone deacetylation complexes to their histone substrates.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolRBBP4
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Short nameRBBP4 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameRBBP4 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameRB binding protein 4, chromatin remodeling factor
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Synonyms gene name
- retinoblastoma-binding protein 4
- retinoblastoma binding protein 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-05-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EMSY complex
- SIN3 histone deacetylase complex subunits
- WD repeat domain containing
- NuRD complex subunits
- Polycomb repressive complex 2
- NURF complex
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data