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CDH17 Antibody

CDH17 Antibody is available 7 times from Abbex labs

abx148801 | CDH17 Antibody size: 200 μg | 467.1 USD

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abx006359 | CDH17 Antibody size: 200 μl | 979.08 USD

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abx148801 | CDH17 Antibody size: 100 μg | 388.87 USD

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abx013917 | CDH17 Antibody size: 200 μg | 526.93 USD

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abx013917 | CDH17 Antibody size: 100 μg | 408.43 USD

Catalog number abx013917
Supplier abbex
Price408.43 USD
Size 100 μg
1. Gene info
Identity1756
GeneCDH17
Long gene name cadherin 17
Synonyms gene name
  • cadherin 17, LI cadherin (liver-intestine)
GenBank acession
Locus8q22.1
Discovery year 1997-02-10
Entrez gene record1015
Pubmed identfication
RefSeq identity
Classification
  • 7D cadherins
Havana BLAST/BLATOTTHUMG00000164391
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedReduced expression of E-cadherin was associated with short overall survival incolorectal neoplasms
High xpression of liver-intestine cadherin and its possible interaction with galectin-3 is associated with ductal adenocarcinoma of the pancreas
LI-cadherin may have a role in lymph node metastasis and progression of human colorectal carcinoma
CDH17 maybe a positive regulator for proliferative, adhesive, and invasive behaviors of gastric cancer.
CDH17 expression may be well preserved during the metastatic process and therefore be a useful marker for identifying colorectal adenocarcinomas in a metastatic setting with an unknown primary site
CDH17 was positively associated with larger tumor size, deeper invasion, diffuse/mixed histotype, LVI, and LNMM, predicting a poor prognosis in pN0 gastric cancer.
Report less aggressive behavior of gastric tumors after CDH17 gene knockdown.
Data suggest that combined tumor expression of CDH17 (cadherin-17) and SATB2 (special AT-rich sequence binding protein 2) may be used as diagnostic biomarkers in subjects with medullary carcinoma of the large intestine (colon; cecum).
These data indicate that knockdown of LIcadherin facilitates the invasion of cancer cells by degrading extracellular matrix components via activation of MMP2 and 9, and increases cancer cell adhesion and migration via altered expression of galectin3.
Using a lentiviral system as a delivery mediator of RNA interference, we found that inhibition of CDH17 can lead to reduce proliferation and increase apoptosis of gastric cancer cell line MKN28 in vitro and significantly diminish their tumorigenicity in vivo. Our results of the present study suggest that CDH17 may be a promising candidate for the therapeutic targeting of gastric cancer.
Entrez Genecadherin 17  (CDH17)
Product images
    Western blot analysis of extracts from Jurkat cells and HUVEC cells, using CDH17 antibody.Immunofluorescence analysis of HeLa cells, using CDH17 antibody.#abx#.jpg

abx006359 | CDH17 Antibody size: 100 μl | 663.84 USD

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abx006359 | CDH17 Antibody size: 50 μl | 486.66 USD

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Clonality Polyclonal
Category Primary Antibodies
Purification Affinity purified
Applications WB (for other applications please contact us)
Footnote This product is for research use only.
Stock availability Shipped within 5-10 working days.
Raised in Rabbit
Target CDH17
Storage conditions Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Immunogen see included datasheet or contact us
Species reactivity Human, Mouse, Rat (for other species please inquire)
Properties If you buy Antibodies supplied by abbex they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetCDH17
Short name CDH17 Antibody
Technique Antibody
Alternative name cadherin 17, LI cadherin (liver-intestine) (Antibody to)
Alternative technique antibodies
Alternative to gene target cadherin 17, LI cadherin (liver-intestine), CDH16 and HPT-1 and HPT1, CDH17 and IDBG-28802 and ENSG00000079112 and 1015, protein binding, Plasma membranes, Cdh17 and IDBG-129666 and ENSMUSG00000028217 and 12557, CDH17 and IDBG-645277 and ENSBTAG00000021964 and 507526
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