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RAF265 for cell activation

RAF265 for cell activation is available 2 times from Biovision labs

2856-5 | RAF265 for cell activation size: 5 mg | 211.04 USD

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2856-25 | RAF265 for cell activation size: 25 mg | 667.14 USD

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Other name 1-Methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl]oxy-N-[4-(trifluoromethyl)phenyl]benzimidazol-2-amine; CHIR265
Supplied with N/A
Description RAF265 (CHIR-265) is a potent and selective inhibitor of C-Raf/B-Raf/B-Raf V600E (IC₅₀ of 3-60 nM); displays potent inhibition on VEGFR2 phosphorylation with EC₅₀ of 30 nM. RAF265 inhibits the growth of advanced human melanoma tumors.
Category Biochemicals
Molecular formula C₂₄H₁₆F₆N₆O
Is it cell-permeable? Yes
Molecular weight 518.41
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 927880-90-8
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance Light yellow to yellow solid
Reconstitute instructions DMSO (>100 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetRAF265 for activation
Short name RAF265 for activation
Technique activation
Alternative name RAF265 to measure cellular activation
Tissue cell
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