Recombinant Human Peroxiredoxin-5/PRDX5 Protein(N-6His)
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Catalog number
PKSH032885-10µg
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Price
Please ask
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Size
10µg
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Synonym
Peroxiredoxin-5; PRDX5; Alu corepressor 1; Antioxidant enzyme B166; AOEB166; Liver tissue 2D-page spot 71B; PLP; Peroxiredoxin V; Prx-V; Peroxisomal antioxidant enzyme; TPx type VI; Thioredoxin peroxidase PMP20; Thioredoxin reductase
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Activity
NA
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Sequence
Met53-Leu214
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Fusion tag
N-6His
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Accession
P30044
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Expressed Host
Human cells
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Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
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Purity
＞95% as determined by reducing SDS-PAGE.
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Endotoxin
＜1.0 EU per µg as determined by LAL test.
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Stability and Storage
Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
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Mol Mass
17.9 kDa
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AP Mol Mass
17 kDa
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Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Background
Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/ahpC family of peroxiredoxins. PRDX5 is a widely expressed mitochondrial antioxidant enzyme that reduces hydrogen peroxide, alkyl hydroperoxides, and peroxynitrite. In human cells, this enzyme is present in the cytosol, mitochondria, peroxisomes, and nucleus.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
PRDX5
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Short name
Recombinant Peroxiredoxin-5/PRDX5 Protein(N-6His)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Human, Humans
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Alternative name
Rec. H. sapiens Peroxiredoxin-5/peroxiredoxin 5 Protein(N-6His)
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Alternative technique
rec
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Alternative to gene target
peroxiredoxin 5, ACR1 and AOEB166 and B166 and HEL-S-55 and PLP and PMP20 and PRDX6 and prx-V and PRXV, PRDX5 and IDBG-53649 and ENSG00000126432 and 25824, peroxynitrite reductase activity, nuclei, Prdx5 and IDBG-136962 and ENSMUSG00000024953 and 54683, PRDX5 and IDBG-643929 and ENSBTAG00000008648 and 282885
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Gene info
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Identity
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Gene
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Long gene name
peroxiredoxin 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2000-07-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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