Recombinant Human Peroxiredoxin 2 / PRDX2 Protein (His tag)

• Catalog number
  PKSH031179-20µg
• Price
  Please ask
• Size
  20µg

• Synonym
  HEL-S-2a;NKEF-B;NKEFB;PRP;PRX2;PRXII;PTX1;TDPX1;TPX1;TSA
• Activity
  Measured by its ability to reduce H2O2.The specific activity is >300 pmoles/min/μg.
• Sequence
  Met 1-Asn 198
• Fusion tag
  N-His
• Accession
  P32119
• Expressed Host
  Baculovirus-Insect Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞92 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  24 kDa
• AP Mol Mass
  27 kDa
• Formulation
  Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 10% gly
• Background
  Peroxiredoxin-2, also known as Natural killer cell-enhancing factor B, NKEF-B, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, PRDX2 and NKEFB, is a cytoplasm protein which belongs to the ahpC / TSA family. Peroxiredoxin-2 / PRDX2 contains one thioredoxin domain. Peroxiredoxin-2 / PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-2 / PRDX2 is not able to receive electrons from glutaredoxin. It may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-2 / PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The Peroxiredoxins / Prx are a family of peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups ( PRDX1，PRDX2, PRDX3, PRDX4, PRDX5, PRDX6 ) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.
• Technical data
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Peroxiredoxin   PRDX2   Protein   His   tag  
• Gene symbol
  PRDX2
• Short name
  Recombinant Peroxiredoxin 2 / PRDX2 Protein (His tag)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Peroxiredoxin 2 / peroxiredoxin 2 Protein (histidine detection labelled)
• Alternative technique
  rec
• Alternative to gene target
  peroxiredoxin 2, HEL-S-2a and NKEF-B and NKEFB and PRP and PRX2 and PRXII and PTX1 and TDPX1 and TPX1 and TSA, PRDX2 and IDBG-31024 and ENSG00000167815 and 7001, peroxiredoxin activity, Cytoplasm, PRDX2 and IDBG-642937 and ENSBTAG00000012062 and 286793

Gene info

• Identity
  HGNC:9353
• Gene
  PRDX2
• Long gene name
  peroxiredoxin 2
• Synonyms gene
  • TDPX1
• Synonyms
  • PRP
  • NKEFB
  • TSA
  • PRXII
  • PRX2
  • MGC4104
• Synonyms name
  • thioredoxin-dependent peroxide reductase 1
  • thiol-specific antioxidant 1
  • natural killer-enhancing factor B
  • thioredoxin peroxidase 1
  • torin
• Locus
  19p13.13
• Discovery year
  1995-07-06
• Entrez gene record
  7001
• Pubmed identfication
  • 7607688
• RefSeq identity
  • NM_005809
• Classification
  • Peroxiredoxins
• VEGA ID
  OTTHUMG00000134285

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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