Other name
N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide; TMP-269
Supplied with
N/A
Description
TMP269 is a potent, selective and cell-permeable class IIa HDAC inhibitor (IC₅₀ values of of 126 nM, 80 nM, 36 nM and 19 nM for HDAC4, HDAC5, HDAC7 and HDAC9 respectively). Displays 20-400 fold selectivity over class I HDACs.
Category
Biochemicals
Molecular formula
C₂₅H₂₁F₃N₄O₃S
Is it cell-permeable?
Yes
Molecular weight
514.52
Storage condition
-20°C
Shipping condition
Gel pack
Purification
≥98% by HPLC
Peptide sequence
N/A
Is this a salt?
No
CAS number
1314890-29-3
Storage instructions
Protect from air and light
Maximum time for storage
36 months
Physical appearance
White to off-white solid
Reconstitute instructions
DMSO (>25 mg/ml)
Additional description
For cells, cell lines and tissues in culture till half confluency.
Gene targetTMP269
for
activation
Short name
TMP269 for activation
Technique
activation
Alternative name
TMP269 to measure cellular activation
Tissue
cell
