Other name
N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide; TMP-269
Supplied with
N/A
Description
TMP269 is a potent, selective and cell-permeable class IIa HDAC inhibitor (IC₅₀ values of of 126 nM, 80 nM, 36 nM and 19 nM for HDAC4, HDAC5, HDAC7 and HDAC9 respectively). Displays 20-400 fold selectivity over class I HDACs.
Category
Biochemicals
Molecular formula
C₂₅H₂₁F₃N₄O₃S
Is it cell-permeable?
Yes
Molecular weight
514.52
Storage condition
-20°C
Shipping condition
Gel pack
Purification
≥98% by HPLC
Peptide sequence
N/A
Is this a salt?
No
CAS number
1314890-29-3
Storage instructions
Protect from air and light
Maximum time for storage
36 months
Physical appearance
White to off-white solid
Reconstitute instructions
DMSO (>25 mg/ml)
Additional description
For cells, cell lines and tissues in culture till half confluency.
