anti-JMJD2A Antibody

• Catalog number
  5373
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  JMJD2A Antibody: Members of the Jumonji domain 2 (JMJD2) family contain a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. The first member of this group, JMJD2A, is widely expressed in human tissues and cell lines and functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. JMJD2A can also form a complex with the androgen receptor (AR), a transcription factor that is pivotal for the development of prostate cancer. Overexpression of JMJD2A stimulates AR function and this stimulation is dependent on JMJD2A catalytic activity, suggesting that JMJD2A might be a critical protein with roles in cell proliferation and oncogenesis.
• Gene names
  JMJD2A Antibody: JMJD2, JHDM3A, JMJD2A, TDRD14A, JMJD2, KIAA0677, Lysine-specific demethylase 4A, JmjC domain-containing histone demethylation protein 3A
• Antibodie s label
  unlabelled serum
• Purity
  JMJD2A Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  JMJD2A antibody was made against a 14 amino acid synthetic peptide from near the center of human JMJD2A.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  JMJD2A antibody can be used for detection of JMJD2A by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL.
• Suspention pH azide
  JMJD2A Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  JMJD2A antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  55665236
• Ncbi nr
  CAH71021
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  9682
• GENE symbol
  KDM4A
• Antigene name
  lysine (K)-specific demethylase 4A
• Source
  Homo sapiens
• Protein nr
  O75164
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  JMJD2A  
• Gene symbol
  KDM4A
• Short name
  anti-JMJD2A Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toJMJD2A (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:22978
• Gene
  KDM4A
• Long gene name
  lysine demethylase 4A
• Synonyms gene
  • JMJD2
  • JMJD2A
• Synonyms gene name
  • jumonji domain containing 2
  • jumonji domain containing 2A
  • lysine (K)-specific demethylase 4A
• Synonyms
  • KIAA0677
  • JHDM3A
  • TDRD14A
• Synonyms name
  • jumonji C domain-containing histone demethylase 3A
  • tudor domain containing 14A
• GenBank acession
  • AB014577
• Locus
  1p34.2-p34.1
• Discovery year
  2003-08-08
• Entrez gene record
  9682
• Pubmed identfication
  • 9734811
  • 15138608
• RefSeq identity
  • NM_014663
• Classification
  • Tudor domain containing
  • Lysine demethylases
• VEGA ID
  OTTHUMG00000007560

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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