Dapagliflozin
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Catalog number9452-50
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PricePlease ask
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Size50 mg
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Alternative_name(1S)-1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol
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DescriptionDapagliflozin is a selective SGLT (sodium-glucose cotransporter) inhibitor that blocks glucose transport with about 100-fold selectivity for SGLT2 (Ki = 6 nM; EC₅₀ = 1.1 nM) over SGLT1 (Ki = 390 nM). An antidiabetic agent.
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CAS Number461432-26-8
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Structure AvailableYes
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Molecular FormulaC₂₁H₂₅ClO₆
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Molecular Weight408.87
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~80 mg/ml) or EtOH (~30 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent and selective selective SGLT-2 (sodium-glucose cotransporter 2) inhibitor
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Storage Condition-20°C
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Shipping ConditionGel pack
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Shelf Life36 months
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MDL NumberMFCD13182359
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PubChem CID9887712
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SMILESCCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl
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InChiInChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1
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InChi KeyJVHXJTBJCFBINQ-ADAARDCZSA-N
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MSDS AvailableYes
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Gene target
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Short nameDapagliflozin
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Alternative nameDapagliflozin
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