Dapagliflozin

  • Catalog number
    9452-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    (1S)-​1,​5-​anhydro-​1-​C-​[4-​chloro-​3-​[(4-​ethoxyphenyl)methyl]phenyl]-​D-​glucitol
  • Description
    Dapagliflozin is a selective SGLT (sodium-glucose cotransporter) inhibitor that blocks glucose transport with about 100-fold selectivity for SGLT2 (Ki = 6 nM; EC₅₀ = 1.1 nM) over SGLT1 (Ki = 390 nM). An antidiabetic agent.
  • CAS Number
    461432-26-8
  • Structure Available
    Yes
  • Molecular Formula
    C₂₁H₂₅ClO₆
  • Molecular Weight
    408.87
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~80 mg/ml) or EtOH (~30 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A potent and selective selective SGLT-2 (sodium-glucose cotransporter 2) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD13182359
  • PubChem CID
    9887712
  • SMILES
    CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl
  • InChi
    InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1
  • InChi Key
    JVHXJTBJCFBINQ-ADAARDCZSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Dapagliflozin
  • Alternative name
    Dapagliflozin
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