BLNK(Tyr84) Antibody, ALEXA FLUOR 647

• Catalog number
  bs-9687R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  BLNK(Tyr84) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-BLNK Tyr84 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  BLNK Tyr84
• Specificity
  This is a highly specific antibody against BLNK Tyr84.
• Modification
  Phosphorylation
• Modification Site
  Tyr84
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human BLNK around the phosphorylation site of Tyr84 [EM(p-Y)VM]
• Gene ID Number
  29760
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  BLNK phospho Y84; p-BLNK phospho Y84; B cell adapter containing SH2 domain protein; B cell adapter containing Src homology 2 domain protein; B cell linker; B cell linker protein; B cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker protein; BASH; BASH; Bca; Bca; BLNK; BLNK s; BLNK_HUMAN; Cytoplasmic adapter protein; Ly 57; Ly-57; Ly57; Lymphocyte antigen 57; Lymphocyte antigen-57; Lyw 57; Lyw-57; Lyw57; MGC111051; SLP 65; SLP65; SLP-65; Src homology 2 domain containing leukocyte protein of 65 kDa.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-BLNK Tyr84 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  BLNK   Tyr84  
• Gene symbol
  BLNK
• Short name
  Anti-BLNK Tyr84
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  BLNK(Tyr84) Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  B-cell linker, BLNK and IDBG-83724 and ENSG00000095585 and 29760, protein binding, Plasma membranes, Blnk and IDBG-165316 and ENSMUSG00000061132 and 17060, BT.24520 and IDBG-638042 and ENSBTAG00000021358 and 510393

Gene info

• Identity
  HGNC:14211
• Gene
  BLNK
• Long gene name
  B cell linker
• Synonyms
  • SLP65
  • Ly57
  • SLP-65
  • BLNK-s
  • BASH
  • bca
• Synonyms name
  • B-cell adapter containing a SH2 domain protein
  • B-cell activation
  • Src homology [SH2] domain-containing leukocyte protein of 65 kD
  • B cell adaptor containing SH2 domain
• GenBank acession
  • AF068180
• Locus
  10q24.1
• Discovery year
  2001-07-16
• Entrez gene record
  29760
• Pubmed identfication
  • 9697839
  • 10583958
• RefSeq identity
  • NM_013314
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000018827
• Locus Specific Databases
  • BLNKbase: Mutation registry for BLNK deficiency
  • LRG_21

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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