anti- TXNDC5 antibody
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Catalog numberFNab09127
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PricePlease ask
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Size2X100μg
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Formliquid
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PurificationImmunogen affinity purified
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.1% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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BackgroundThis gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
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Immunogenthioredoxin domain containing 5 (endoplasmic reticulum)
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SynonymsEndoPDI, ER protein 46, ERP46, Hcc 2, PDIA15, Thioredoxin like protein p46, TLP46, TXNDC5, UNQ364
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Calculated MWRefer to figures
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Uniprot IDQ8NBS9
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SpecificityHuman, Mouse, Rat
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Tested ApplicationELISA, WB, IHC, IF
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Recommended dilutionWB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
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Image1Immunohistochemistry of paraffin-embedded human colon cancer using FNab09127(TXNDC5 antibody) at dilution of 1:100
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Image4HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09127(TXNDC5 antibody) at dilution of 1:1000
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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PropertiesIf you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolBLOC1S5-TXNDC5, TXNDC5
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Short nameanti- TXNDC5 antibody
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TechniqueAntibody, anti, antibody to, antibodies against human proteins, antibodies for
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HostRabbit
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IsotypeIgG
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Alternative nameantibody to- thioredoxin domain containing 5 (endoplasmic reticulum) (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetthioredoxin domain containing 5 (endoplasmic reticulum), TXNDC5 and IDBG-408882 and ENSG00000239264 and 81567, isomerase activity, multiple, Txndc5 and IDBG-145980 and ENSMUSG00000038991 and 105245, TXNDC5 and IDBG-636334 and ENSBTAG00000019237 and 615027
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Gene info
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Identity
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Gene
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Long gene nameBLOC1S5-TXNDC5 readthrough (NMD candidate)
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Synonyms gene
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Synonyms gene name
- MUTED-TXNDC5 readthrough (non-protein coding)
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Locus
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Discovery year2011-05-31
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Entrez gene record
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namethioredoxin domain containing 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-05-15
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Entrez gene record
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RefSeq identity
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Classification
- Protein disulfide isomerases
- Thioredoxin domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data