AP-18, TRPA1 blocker

• Catalog number
  SIH-310-10MG
• Price
  Please ask
• Size
  10 mg

• Stock availabilitIn Stock
  In Stock
• CAS number
  55224-94-7
• Description
  TRPA1 blocker
• Molecular weight
  209,67 g/mol
• Primary research fields
  Neuroscience, Ion Channels, Transient Receptor Potential Channels
• Other name
  (2E,3E)-4-(4-Chlorophenyl)-N-hydroxy-3-methyl-3-buten-2-imine
• Product category
  Small Molecules
• Product type
  Inhibitor
• Chemical formula
  C11H12ClNO
• Origin
  Synthetic
• Purity pourcentage
  >98%
• Soluble in
  Soluble to 100 mM in DMSO and to 100 mM in ethanol
• Physical appearance
  White Solid
• Storage recommendations
  -20ºC
• Shipping recommendations
  Shipped Ambient
• Safety information
  Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
• PubChem number
  16725814
• Scientific context
  AP-18 is a reversible TRPA1 channel blocker. They exhibit fibroblast-like morphology, slow growth and contact inhibition (1).
• Bibliography
  1. Doi H., et al. (2005) Tohoku J Exp Med. 207(3): 209-216.
• Release date
  8-Apr-2011
• PubMed number
  Refer to PubMed
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• Representative figure link
• Representative figure legend
  Chemical structure of AP-18 (SIH-310), a TRPA1 blocker. CAS #: 55224-94-7. Molecular Formula: C11H12ClNO. Molecular Weight: 209.67 g/mol. Chemical structure of AP-18, a TRPA1 blocker (SIH-310). CAS # 55224-94-7. Molecular Formula: C11H12ClNO.
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  0.25
• Net weight g
  0.01
• Other related products

• Gene target
  AP-18   TRPA1   blocker  
• Gene symbol
  TRPA1, SNORD114-18, PIRC96, SNORD116-18, IGLV2-18, IGHV1-18, JUND, SNORD115-18, ERVW-18
• Short name
  AP-18, TRPA1 blocker
• Label
  AP
• Alternative name
  AP-18, TRPA1 blocker

Gene info

• Identity
  HGNC:497
• Gene
  TRPA1
• Long gene name
  transient receptor potential cation channel subfamily A member 1
• Synonyms gene
  • ANKTM1
• Synonyms gene name
  • ankyrin-like with transmembrane domains 1
  • transient receptor potential cation channel, subfamily A, member 1
• GenBank acession
  • Y10601
• Locus
  8q21.11
• Discovery year
  1999-01-15
• Entrez gene record
  8989
• Pubmed identfication
  • 16382100
• RefSeq identity
  • NM_007332
• Classification
  • Ankyrin repeat domain containing
  • Transient receptor potential cation channels
• VEGA ID
  OTTHUMG00000164516

Gene info

• Identity
  HGNC:33006
• Gene
  SNORD114-18
• Long gene name
  small nucleolar RNA, C/D box 114-18
• Synonyms
  • 14q(II-18)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767596
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003211.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:37600
• Gene
  PIRC96
• Long gene name
  piwi-interacting RNA cluster 96
• Locus
  18
• Discovery year
  2009-11-05
• Entrez gene record
  100313800
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33084
• Gene
  SNORD116-18
• Long gene name
  small nucleolar RNA, C/D box 116-18
• Synonyms
  • HBII-85-18
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033430
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003333
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5889
• Gene
  IGLV2-18
• Long gene name
  immunoglobulin lambda variable 2-18
• GenBank acession
  • Z73642
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28814
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151232

Gene info

• Identity
  HGNC:5549
• Gene
  IGHV1-18
• Long gene name
  immunoglobulin heavy variable 1-18
• GenBank acession
  • M99641
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28468
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152276

Gene info

• Identity
  HGNC:6206
• Gene
  JUND
• Long gene name
  JunD proto-oncogene, AP-1 transcription factor subunit
• Synonyms
  • AP-1
• Synonyms name
  • transcription factor jun-D
  • JunD-FL isoform
  • activator protein 1
• Locus
  19p13.11
• Discovery year
  1990-09-10
• Entrez gene record
  3727
• Pubmed identfication
  • 2112242
  • 1903194
• RefSeq identity
  • NM_005354
• Classification
  • Basic leucine zipper proteins
  • Jun transcription factor family
• VEGA ID
  OTTHUMG00000183355

Gene info

• Identity
  HGNC:33037
• Gene
  SNORD115-18
• Long gene name
  small nucleolar RNA, C/D box 115-18
• Synonyms
  • HBII-52-18
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033456
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003310.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:49306
• Gene
  ERVW-18
• Long gene name
  endogenous retrovirus group W member 18
• Synonyms gene name
  • endogenous retrovirus group W, member 18
• GenBank acession
  • HG421056
• Locus
  6q24.2
• Discovery year
  2013-10-21

Similar products