Rabbit Anti Rat Mapt Antibody-Biotin

• Catalog number
  CSB-PA013481YD01RA_50ug
• Price
  Please ask
• Size
  50ug

• Long name
  Rabbit Antibody against Rat Mapt, Biotin
• Synonym name
  Mapt Rat Antibody
• Species reactivity
  Rat
• Tested applications recommended dilutions
  ELISA
• Conjugation
  Biotin
• Antibody isotype
  IgG
• UniProt ID
  P19332
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant rat Microtubule-associated protein tau protein (2-752AA)
• Immunogen species
  Rat
• Alias
  Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, Mapt, Mtapt, Tau
• Background
  Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
• Clonality
  Polyclonal antibody
• Shipping and storage
  Mapt Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Oryctolagus cuniculus, Rattus norvegicus
• French translation
  anticorps

• Gene target
  Mapt  
• Gene symbol
  MAPT-AS1, MAPT-IT1, STH
• Short name
  Anti-Mapt
• Technique
  Antibody, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit, Rabbits
• Label
  Biotin
• Species
  Rat, Rats
• Alternative name
  Mapt Antibody,Biotin conjugated
• Alternative technique
  antibodies, rabbit-anti

Gene info

• Identity
  HGNC:43738
• Gene
  MAPT-AS1
• Long gene name
  MAPT antisense RNA 1
• Synonyms gene name
  • MAPT antisense RNA 1 (non-protein coding)
• Locus
  17q21.31
• Discovery year
  2012-02-17
• Entrez gene record
  100128977
• Pubmed identfication
  • 27336847
• RefSeq identity
  • NR_024559
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000178246

Gene info

• Identity
  HGNC:43741
• Gene
  MAPT-IT1
• Long gene name
  MAPT intronic transcript 1
• Synonyms gene name
  • MAPT intronic transcript 1 (non-protein coding)
• Locus
  17q21.31
• Discovery year
  2012-02-20
• Entrez gene record
  100130148
• RefSeq identity
  • NR_024560
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000177993

Gene info

• Identity
  HGNC:18839
• Gene
  STH
• Long gene name
  saitohin
• Synonyms
  • MAPTIT
• Synonyms name
  • microtubule-associated protein tau (MAPT) intronic transcript
• GenBank acession
  • AA325304
• Locus
  17q21.31
• Discovery year
  2008-01-22
• Entrez gene record
  246744
• Pubmed identfication
  • 12032355
  • 16186110
• VEGA ID
  OTTHUMG00000168633

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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