Phospho-PDGFR beta (Tyr716) polyconal Antibody

• Catalog number
  A1035-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  PDGFR
• Target Alternative Name
  PDGFRB; PDGFR; PDGFR1; Platelet-derived growth factor receptor beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthetic peptide
• Accession
  P16234
• Gene Id
  5156
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  100 ug (1 mg/ml) of antibody in 0.01M Tris-HCl, pH 8.0, 0.15M NaCl, and 0.02% sodium azide.
• Purification
  Affinity purified rabbit IgG using protein G
• Application
  WB, Immunoblot, ELISA
• Application And Usages
  Western blot, Immunoblot: 0.5-2 μg/ml, ELISA
• Description
  Platelet-derived growth factor (PDGF) refers to a family of disulphide-bonded dimeric isoforms that are important for growth and survival, and which function in several types of connective tissue cell. There are four members of the platelet-derived growth factor (PDGF) family: PDGF-A, PDGF-B, PDGF-C and PDGF-D (spinal cord-derived growth factor-B or iris-expressed growth factor). Their biological effects are mediated via two tyrosine kinase receptors, PDGFR-α and PDGFR-β. PDGF-mediated signaling is critical for development of many organ systems. PDGF-D has a two-domain structure similar to PDGF-C and is secreted as a disulphide-linked homodimer, PDGF-DD. Upon limited proteolysis, PDGF-DD is activated and becomes a specific agonistic ligand for PDGFR-β. PDGF-D is expressed in fibroblastic adventitial cells, cultured endothelial cells and in a variety of tumor cell lines.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Not Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Phospho-PDGFR   beta   Tyr716   polyconal  
• Gene symbol
  PDGFRB
• Short name
  Phospho-PDGFR beta (Tyr716) polyconal Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  phosphorilated-PDGFR b (Tyr716) polyconal (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8804
• Gene
  PDGFRB
• Long gene name
  platelet derived growth factor receptor beta
• Synonyms gene
  • PDGFR
• Synonyms gene name
  • platelet-derived growth factor receptor, beta polypeptide
• Synonyms
  • JTK12
  • CD140b
  • PDGFR1
• GenBank acession
  • M21616
• Locus
  5q32
• Discovery year
  2001-06-22
• Entrez gene record
  5159
• RefSeq identity
  • NM_002609
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • I-set domain containing
• VEGA ID
  OTTHUMG00000130053

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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