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anti PlGF Antibody

anti PlGF Antibody is available 2 times from Biovision labs

5743-100 | anti-PlGF Antibody size: PlGF Antibody | 387.69 USD

Catalog number 5743-100
Supplier Biovision
Price387.69 USD
Size PlGF Antibody
Formulation of this antibody: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
1. Gene info
Long gene name placental growth factor
Synonyms gene name
  • placental growth factor-like
  • placental growth factor, vascular endothelial growth factor-related protein
GenBank acession
Discovery year 1994-01-14
Entrez gene record5228
Pubmed identfication
RefSeq identity
  • VEGF family
Havana BLAST/BLATOTTHUMG00000171496
MeSH Data
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedPatients with late-onset preeclampsia (PE) and placental underperfusion had a lower median plasma concentration of PlGF, plasma PlGF/sVEGFR-1 ratio and plasma PlGF/sEng ratio than those with late-onset PE without placental underperfusion lesions.
PIGF is involved in the pathomechanism of preeclampsia and its maternal serum concentration decreases significantly in the course of the disease.
PlGF-mediated increased FLAP mRNA expression occurred via activation of phosphoinositide-3 (PI-3) kinase, nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, and hypoxia inducible factor-1alpha (HIF-1alpha).
Increased circulating placental growth factor during percutaneous coronary intervention is associated with applied radiocontrast agent.
role of PlGF in placentation: Data suggest that in some women with habitual miscarriage, antagonism of beta2-GPI by autoantibodies against beta2-GPI suppresses PlGF production in trophoblasts and causes failure of placenta formation/function.
PlGF, but not VEGF-A was associated with axillary lymph node status and tumor grade was only associated with VEGF-A.
Data suggest that identifying women with consistently low plasma placental growth factor (PGF) during pregnancy may provide a greater understanding of preeclampsia pathophysiology and may provide more focused research and clinical activities.
Maternal placental growth factor rs1042886 polymorphism is associated with preeclampsia in Sinhalese women in Sri-Lanka
Data suggest that maternal serum PGF level in early second trimester (20-22 weeks of gestation) is useful in predicting occurrence of early onset preeclampsia and/or early onset intrauterine growth restriction.
Serum Flt1/PlGF differs significantly among mild and severe pre-eclampsia and gestational proteinuria disorders.
Gene ontology - Cellular componentextracellular space
extracellular region
Product images
    #0#.jpegPlGF Antibody

5743-30T | anti-PlGF Antibody size: PlGF Antibody | 168.61 USD

This antibody has been succesfully tested for use in following methods: Western blot
Target of this antibody: PIGF
Alternative names of antibody target: PIGF1, PIGF 1, PIGF-1, Phosphatidylinositol glycan biosynthesis class F, PIG F
Recommended usage: Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been determined.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
Antibody host: Rabbit
This antibody reacts with: Mouse
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
Purification method: Affinity purified
Immunogene sequence: E. coli expressed mouse PLGF
How to handle this antibody: The antibody solution should be gently mixed before use.
Background information: PLGF (also called Placenta Growth Factor, PIGF, PGF) is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF is expressed in placental tissues, colon and mammary carcinomas. It signals throμgh the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant mouse PLGF is a disulfide-linked homodimer containing two 142 amino acid polypeptide chains.
Form of antibody: Liquid
Concentration of antibody: 0.5 mg/ml
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetPlGF
Short name anti-PlGF Antibody
Technique Antibody, anti
Alternative name antibody to-PlGF (Antibody to)
Alternative technique antibodies
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