Monoclonal Antibody (Clone#1H9-D3-E11)
Mouse Monoclonal antibody to detect Cyclin H
Cyclin-H (Cyclin-H, MO15-associated protein, p34, p37)
Affinity purified antibody is supplied in liquid form in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Recombinant human Cyclin H protein fragments expressed in E.coli
Manifactured in USA. For Research Use Only! Not to be used in humans
This antibody is available to order since May 2017
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Approved applications with antibody dilution
Western blot; 1:1000, Immunoprecipitation
Handling and storage
Before use gently mix the antibody solution. Store this antibody at -20 °C for 12 months. Refer to the label on vial
Antibody's positive controles
Western blot: Jurkat, K562 and A431 cell lysates; Immunoprecipitation: HeLa cell lysates
Shipped to your lab under gel pack
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Mouse Monoclonal Anti-Cyclin H Antibody (1H9-D3-E11)
Mouse monoclonal, Antibody, Mouse, anti
Mouse monoclonal antibody to-Cyclin H (Antibody to) (1H9-D3-E11)