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Mouse Monoclonal Anti-Cyclin H Antibody (1H9-D3-E11)

Mouse Monoclonal Anti-Cyclin H Antibody (1H9-D3-E11) is available 1 time from Biovision labs

A1320-100 | Mouse Monoclonal Anti-Cyclin H Antibody (1H9-D3-E11) size: 100 µg | 383.49 USD

1. Gene info
Identity11160
GeneSNRPD3
Long gene name small nuclear ribonucleoprotein D3 polypeptide
Synonyms gene name
  • small nuclear ribonucleoprotein D3 polypeptide (18kD)
  • small nuclear ribonucleoprotein D3 polypeptide 18kDa
Synonyms
GenBank acession
Discovery year 1995-04-26
Entrez gene record6634
Pubmed identfication
RefSeq identity
Classification
  • Sm spliceosomal proteins
Havana BLAST/BLATOTTHUMG00000150727
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
Entrez GeneDNA segment, 1h9  (HLA-DOA)
Product images
    #0#.jpegAnti-Cyclin H Antibody (1H9-D3-E11)Anti-Cyclin H Antibody (1H9-D3-E11)Anti-Cyclin H Antibody (1H9-D3-E11)#Mouse#.jpg
Clonality Monoclonal Antibody (Clone#1H9-D3-E11)
Description Mouse Monoclonal antibody to detect Cyclin H
Physical state Colorless liquid
Purity Affinity purified
Raised in Mouse
Gene number 902
Target Cyclin-H (Cyclin-H, MO15-associated protein, p34, p37)
Package form Affinity purified antibody is supplied in liquid form in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Immunogen Recombinant human Cyclin H protein fragments expressed in E.coli
Protein number P51946
Precautions Manifactured in USA. For Research Use Only! Not to be used in humans
Released This antibody is available to order since May 2017
Scientific context Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Approved applications with antibody dilution Western blot; 1:1000, Immunoprecipitation
Handling and storage Before use gently mix the antibody solution. Store this antibody at -20 °C for 12 months. Refer to the label on vial
Antibody's positive controles Western blot: Jurkat, K562 and A431 cell lysates; Immunoprecipitation: HeLa cell lysates
Reacts with Human
Research area Cell Cycle
Delivery Shipped to your lab under gel pack
Additional description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
About Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name Mus musculus
French translation anticorps
Short name Mouse Monoclonal Anti-Cyclin H Antibody (1H9-D3-E11)
Technique Mouse monoclonal, Antibody, Mouse, anti
Host mouse monoclonal
Species Mouse
Alternative name Mouse monoclonal antibody to-Cyclin H (Antibody to) (1H9-D3-E11)
Alternative technique antibodies
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