Factor Related Apoptosis (FAS) Polyclonal Antibody (Rat)

• Catalog number
  PAA030Ra02-10ml
• Price
  Please ask
• Size
  10ml

• Description
  A Rabbit polyclonal antibody against Rat Factor Related Apoptosis (FAS)
• Specifications
  Host: Rabbit; Species Reactivity: Rat; Clonality: polyclonal; Tested applications: WB, IHC; Concentration: 500ug/ml; Isotype: IgG; Conjugation: Unconjugated
• Additional_information
  Sequence of the immunogen: FAS (Met21~Lys170); Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
• Storage_and_shipping
  Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
• Notes
  Research Use Only.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Additional description
  This 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• French translation
  anticorps

• Gene target
  Factor   Related   FAS  
• Gene symbol
  FAS-AS1, FASN, FAS
• Short name
  Factor Apoptosis (FAS) Polyclonal Antibody ( )
• Technique
  Polyclonal, apoptosis, Antibody, antibodies against human proteins, antibodies for, apoptosis pathway, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rat
• Species
  Rat, Rats
• Alternative name
  Factor Related programmed cellular destruction (Fas (tumor necrosis factor receptor superfamily, member 6)) polyclonal (antibody to-) (Rat)
• Alternative technique
  polyclonals, celldeath, antibodies
• Alternative to gene target
  Fas (TNF receptor superfamily, member 6), ALPS1A and APO-1 and APT1 and CD95 and FAS1 and FASTM and TNFRSF6, FAS and IDBG-81669 and ENSG00000026103 and 355, identical protein binding, nuclei, Fas and IDBG-159577 and ENSMUSG00000024778 and 14102, FAS and IDBG-637356 and ENSBTAG00000010785 and 282488

Gene info

• Identity
  HGNC:37128
• Gene
  FAS-AS1
• Long gene name
  FAS antisense RNA 1
• Synonyms gene
  • FASAS
  • FAS-AS
• Synonyms gene name
  • FAS antisense RNA (non-protein coding)
  • FAS antisense RNA 1 (non-protein coding)
• Synonyms
  • SAF
• Locus
  10q23.31
• Discovery year
  2009-07-16
• Entrez gene record
  100302740
• Pubmed identfication
  • 15829500
  • 24811343
  • 27141526
• RefSeq identity
  • NR_028371
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:3594
• Gene
  FASN
• Long gene name
  fatty acid synthase
• Synonyms
  • FAS
  • SDR27X1
• Synonyms name
  • short chain dehydrogenase/reductase family 27X, member 1
• GenBank acession
  • U26644
• Locus
  17q25.3
• Discovery year
  1994-05-17
• Entrez gene record
  2194
• Pubmed identfication
  • 7835891
  • 7567999
  • 19027726
• RefSeq identity
  • NM_004104
• Classification
  • Short chain dehydrogenase/reductase superfamily
  • 7BS orphan methyltransferases
• VEGA ID
  OTTHUMG00000178527

Gene info

• Identity
  HGNC:11920
• Gene
  FAS
• Long gene name
  Fas cell surface death receptor
• Synonyms gene
  • FAS1
  • APT1
  • TNFRSF6
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 6
  • Fas (TNF receptor superfamily, member 6)
• Synonyms
  • CD95
  • APO-1
• Synonyms name
  • TNF receptor superfamily member 6
• GenBank acession
  • M67454
• Locus
  10q23.31
• Discovery year
  1992-06-25
• Entrez gene record
  355
• Pubmed identfication
  • 1385299
  • 1385309
• Classification
  • Tumor necrosis factor receptor superfamily
  • Death inducing signaling complex
  • CD molecules
• VEGA ID
  OTTHUMG00000018701
• Locus Specific Databases
  • Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS
  • LOVD at NCBI
  • LRG_134

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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