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Organism Species
Mus musculus (Mouse)
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Source
Polyclonal antibody preparation
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Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
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Buffer Formulation
PBS, pH7.4,containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Item Name
Advanced Glycosylation End Product Specific Receptor
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Immunogen
RPA645Mu01-Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)
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Image number
3
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Species reactivity
Mouse,Rat
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Sequence of immunogen
AGER (Trp10~Arg188)
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Aplication
WB,IHC
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Clonality
Rabbit polyclonal
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Concentration
500ug/ml
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Alternative Names
RAGE; Receptor For Advanced Glycation Endproducts
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Applicable Secondary Antibody
SAA544Rb59, SAA544Rb58, SAA544Rb57, SAA544Rb18, SAA544Rb19
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Delivery condition
4℃ with ice bags
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Storage instructions
Avoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Test
Glycosylation (see also chemical glycosylation) is the reaction in which a carbohydrate, i.e. a glycosylic donor, is attached to a hydroxyl or other functional group of another molecule (a glycosylic acceptor). In biology glycosylation mainly refers in particular to the enzymatic process that attaches glycans to proteins, lipids, or other organic molecules
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by Cloud Clone Corp. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cloud Clone Corp adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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French translation
anticorps
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Gene target
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Gene symbol
AGER
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Short name
Anti-Advanced Glycosylation End Product Specific Receptor (AGER)-Rabbit polyclonal Antibody
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Technique
Polyclonal, Antibody, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Rabbit, Rabbits
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Alternative name
Antibody toAdvanced Glycosylation End reagent Specific Receptor (advanced glycosylation end product-specific receptor)-production species: rabbit polyclonal (antibody to-)
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Alternative technique
polyclonals, antibodies, rabbit-anti
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Alternative to gene target
advanced glycosylation end product-specific receptor, RAGE, AGER and IDBG-80463 and ENSG00000204305 and 177, S100 protein binding, Extracellular, Ager and IDBG-172144 and ENSMUSG00000015452 and 11596, AGER and IDBG-633065 and ENSBTAG00000014420 and 280986
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