MEC/CCL28, human recombinant

• Catalog number
  7170-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  Mucosae-associated Epithelial Chemokine, CCL28, CCK-1
• Alternative_names
  Mucosae-associated Epithelial Chemokine, CCL28, CCK-1
• Description
  Chemoattracts resting CD4, CD8 T cells and eosinophils
• Recombinant
  Yes
• Source
  E. Coli
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 0.1 ng/ug of protein (
• Activity Specifications test method
  Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml.
• Biological activity
  Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml.
• Molecular Weight
  12.3 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized powder
• Physical form description
  Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Acetic Acid.
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
• Background Information
  MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor and chemoattracts resting CD4, CD8 T cells and eosinophils. MEC contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant human MEC is a 12.3 kDa protein containing 108 amino acid residues.
• Amino acid sequence
  SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  MEC/CCL28  
• Gene symbol
  CCL28, FBXW9
• Short name
  MEC/CCL28, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  MEC/chemokine (C-C motif) ligand 28, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  chemokine (C-C motif) ligand 28, CCL28 and IDBG-19270 and ENSG00000151882 and 56477, chemokine activity, Extracellular, Ccl28 and IDBG-705098 and ENSMUSG00000074715 and 56838, CCL28 and IDBG-629570 and ENSBTAG00000001557 and 535328

Gene info

• Identity
  HGNC:17700
• Gene
  CCL28
• Long gene name
  C-C motif chemokine ligand 28
• Synonyms gene name
  • chemokine (C-C motif) ligand 28
• Synonyms
  • SCYA28
  • MEC
  • CCK1
• Synonyms name
  • CC chemokine CCL28
  • mucosae-associated epithelial chemokine
  • small inducible cytokine subfamily A (Cys-Cys), member 28
  • small inducible cytokine A28
• GenBank acession
  • AF110384
• Locus
  5p12
• Discovery year
  2002-08-22
• Entrez gene record
  56477
• Pubmed identfication
  • 10781587
  • 11295038
• RefSeq identity
  • NM_148672
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000094811

Gene info

• Identity
  HGNC:28136
• Gene
  FBXW9
• Long gene name
  F-box and WD repeat domain containing 9
• Synonyms gene name
  • F-box and WD-40 domain protein 9
• Synonyms
  • MGC10870
  • Fbw9
  • MEC-15
• GenBank acession
  • BC004290
• Locus
  19p13.13
• Discovery year
  2004-06-15
• Entrez gene record
  84261
• Pubmed identfication
  • 23527112
• RefSeq identity
  • NM_032301
• Classification
  • WD repeat domain containing
  • F-box and WD repeat domain containing
• VEGA ID
  OTTHUMG00000150152

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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