SLK Antibody

• Catalog number
  3746-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  SLK
• Target Alternative Name
  SLK, STE20-like Kinase, SLK, Sucrose nonfermenting like kinase, STK2, Serine/Threonine Kinase 2
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse
• Immunogen Sequence
  Synthetic peptide of human SLK
• Accession
  NP_055535.2
• Gene Id
  9748
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Immunoprecipitation
• Application And Usages
  Western blotting (1:500 – 1:2500) and immunoprecipitation. However, the optimal concentrations should be determined individually. The antibody recognizes the SLK of human and mouse origin. Reactivity to other species has not been tested.
• Description
  SLK (STE20-like kinase), also known as STK2 (serine/threonine protein kinase 2) or se20-9, is a member of the serine/threonine kinase subfamily, Ste20. This subfamily is comprised of several mammalian kinases which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase Ste20, a protein involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Members of this subfamily include KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, GC kinase, HGK and SLK. SLK is a ubiquitously expressed protein that localizes to the cytoplasm and contains an N-terminal protein kinase domain, a central coiled-coil domain and a C-terminal ATH domain. SLK is activated through cleavage by caspase-3. SLK indirectly associates with microtubules and plays an important role in cellular stress, cell motility, cell death and cytoskeletal dynamics.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SLK  
• Gene symbol
  FYN, SLK
• Short name
  SLK Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  STE20-like kinase (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  STE20-like kinase, bA16H23.1 and LOSK and se20-9 and STK2, SLK and IDBG-88663 and ENSG00000065613 and 9748, transferase activity, Cytoplasm, Slk and IDBG-174800 and ENSMUSG00000025060 and 20874, SLK and IDBG-639375 and ENSBTAG00000001017 and 535342

Gene info

• Identity
  HGNC:4037
• Gene
  FYN
• Long gene name
  FYN proto-oncogene, Src family tyrosine kinase
• Synonyms gene name
  • FYN oncogene related to SRC, FGR, YES
• Synonyms
  • SYN
  • SLK
  • MGC45350
• GenBank acession
  • AK056699
• Locus
  6q21
• Discovery year
  1988-08-19
• Entrez gene record
  2534
• Pubmed identfication
  • 3526330
• Classification
  • Src family tyrosine kinases
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000016305

Gene info

• Identity
  HGNC:11088
• Gene
  SLK
• Long gene name
  STE20 like kinase
• Synonyms gene name
  • SNF1 (sucrose nonfermenting, yeast, homolog)-like kinase, SNF1 sucrose nonfermenting like kinase (yeast)
  • STE20-like kinase (yeast)
  • STE20-like kinase
• Synonyms
  • STK2
  • se20-9
  • KIAA0204
• Locus
  10q24.33-q25.1
• Discovery year
  1992-04-16
• Entrez gene record
  9748
• Pubmed identfication
  • 3526554
• RefSeq identity
  • NM_014720
• VEGA ID
  OTTHUMG00000018999

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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