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Long name
Mouse Monoclonal Antibody against Human IgA secretory component, Clone: SC-05
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Antigen
IgA secretory component
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Species reactivity
Human (Homo sapiens)
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Negative species reactivity
at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
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Clonality
Monoclonal Antibody (Mab)
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Clone
SC-05
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Applications
IP, WB, IHC(P), IHC(F)
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Immunogen
Affinity-purified secretory component from human colostrum.
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Format conjugation
purified; unconjugated
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Specificity
The antibody SC-05 reacts with 80 kDa human secretory component glycoprotein (both free and bound in secretory IgA). Recognized glycoprotein is specific membrane marker of glandular carcinomas.
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Research area
Miscellaneous (Human), Immunoglobulins (Human)
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Concentration
1 mg/ml
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Storage buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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Shipping and storage
Mouse Monoclonal Antibody against Human IgA secretory component, Clone: SC-05 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
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Purity
> 95% (by SDS-PAGE)
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Purification method
Purified by protein-A affinity chromatography
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References
*Bartek J, Bartkova J, Taylor-Papadimitriou J: Keratin 19 expression in the adult and developing human mammary gland. Histochem J. 1990 Oct;22(10):537-44. _x000D_ , *Bartek J, Tlaskalova-Hogenova H, Staskova Z, Simeckova J, Vojtesek B, Rejthar A, Kovarik J, Bartkova J: Secretory component in differentiating normal epithelium, benign lesions and malignancy in the human breast as monitored by monoclonal antibodies. Histochemistry. 1989;91(3):235-44. _x000D_ , *Kvale D, Bartek J, Sollid LM, Brandtzaeg P: Rapid selection of cultured cells with increased expression of a membrane_x000D_ marker (secretory component). Int J Cancer. 1988 Oct 15;42(4):638-41. _x000D_
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Properties
If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Immunoglobulin A (IgA, also referred to as sIgA) is an antibody that plays a critical role in immune function in the mucous membranes. More IgA is produced in mucosal linings than all other types of antibody combined. Examples are EMA, ACA ELISA test kits and for diagnostic detection the IgA of Anti-Beta-2 Glycoprotein 1; β2-Glycoprotein 1 Antibodies; Beta 2GP1 Ab, Beta-2 Glycoprotein 1 Antibodies IgG, IgM, and IgAs.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translation
anticorps