Chk2 Antibody

  • Catalog number
    3305-100
  • Price
    Please ask
  • Size
    100 µg
  • Antibody Target
    Chk2
  • Target Alternative Name
    CHEK2 , CHK2 , CDS1 , RAD53 , LFS2 , HuCds1, PP1425, OTTHUMP00000028871
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, mouse, rat
  • Immunogen Sequence
    Synthetic peptide corresponding to amino acid near the N-terminus of human Chk2
  • Accession
    O96017
  • Gene Id
    11200
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    100 µg (0.5 mg/ml) affinity purified rabbit anti-Chk2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
  • Purification
    Affinity purified
  • Application
    Western blot, Immunofluorescence
  • Application And Usages
    Western blotting (0.5-4 µg/ml) and immunofluorescence (5-10 µg/ml). However, the optimal conditions should be determined individually.
  • Description
    Chk2 is the mammalian homologue of yeast Cds1/Rad53. In response to DNA damage, a checkpoint kinase ATM phosphorylates and activates Chk2, which in turn phosphorylates and activates p53. Chk2 also phosphorylates and activates BRCA1, the product of a tumor suppressor gene that is mutated in breast and ovarian cancer.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    Chk2  
  • Gene symbol
    CHEK2, ATMIN, CHEK2P1
  • Short name
    Chk2 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    Chk2 (antibody to-)
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    CHEK2 pseudogene 1
  • Synonyms gene
  • Synonyms gene name
    • CHK2 checkpoint homolog (S. pombe)-like 1
    • checkpoint kinase 2 pseudogene 1
  • Locus
  • Discovery year
    2010-06-30
  • Entrez gene record
  • RefSeq identity
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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