Chk2 Antibody
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Catalog number3305-100
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PricePlease ask
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Size100 µg
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Antibody TargetChk2
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Target Alternative NameCHEK2 , CHK2 , CDS1 , RAD53 , LFS2 , HuCds1, PP1425, OTTHUMP00000028871
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat
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Immunogen SequenceSynthetic peptide corresponding to amino acid near the N-terminus of human Chk2
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AccessionO96017
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Gene Id11200
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulation100 µg (0.5 mg/ml) affinity purified rabbit anti-Chk2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
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PurificationAffinity purified
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ApplicationWestern blot, Immunofluorescence
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Application And UsagesWestern blotting (0.5-4 µg/ml) and immunofluorescence (5-10 µg/ml). However, the optimal conditions should be determined individually.
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DescriptionChk2 is the mammalian homologue of yeast Cds1/Rad53. In response to DNA damage, a checkpoint kinase ATM phosphorylates and activates Chk2, which in turn phosphorylates and activates p53. Chk2 also phosphorylates and activates BRCA1, the product of a tumor suppressor gene that is mutated in breast and ovarian cancer.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCHEK2, ATMIN, CHEK2P1
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Short nameChk2 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameChk2 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecheckpoint kinase 2
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Synonyms gene
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Synonyms gene name
- CHK2 (checkpoint, S.pombe) homolog
- CHK2 checkpoint homolog (S. pombe)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-09-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameATM interactor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2007-12-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2H2-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCHEK2 pseudogene 1
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Synonyms gene
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Synonyms gene name
- CHK2 checkpoint homolog (S. pombe)-like 1
- checkpoint kinase 2 pseudogene 1
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Locus
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Discovery year2010-06-30
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Entrez gene record
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RefSeq identity
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data