TRIM50 Antibody

• Catalog number
  bs-9152R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TRIM50 Primary Polyclonal Antibody
• Also known as
  TRIM50 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TRIM50
• Specificity
  This is a highly specific antibody against TRIM50.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRIM50
• Gene ID number
  135892
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM50 (tripartite motif containing 50), also known as TRIM50A or E3 ubiquitin-protein ligase TRIM50, is a 487 amino acid cytoplasmic protein that functions as an E3 ubiquitin-protein ligase. Containing one RING-type zinc finger, a B30.2/SPRY domain and a single B box-type zinc finger, TRIM50 belongs to the TRIM/RBCC family and undergoes post-translational auto-ubiquitination. TRIM50 exists as two alternatively spliced isoforms, designated TRIM50 alpha and TRIM50 beta, and has the ability to form dimers and trimers. The gene encoding TRIM50 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  E3 ubiquitin ligase; E3 ubiquitin protein ligase TRIM50; TRIM50A; Tripartite mot containing protein 50; tripartite mot protein 50A; tripartite mot-containing 50A; TRI50_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRIM50  
• Gene symbol
  TRIM50
• Short name
  Anti-TRIM50
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TRIM50 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19017
• Gene
  TRIM50
• Long gene name
  tripartite motif containing 50
• Synonyms gene
  • TRIM50A
• Synonyms gene name
  • tripartite motif-containing 50A
  • tripartite motif-containing 50
• Synonyms
  • FLJ32804
• GenBank acession
  • AY081948
• Locus
  7q11.23
• Discovery year
  2002-08-29
• Entrez gene record
  135892
• RefSeq identity
  • NM_178125
• Classification
  • Tripartite motif containing
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000156805

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products