anti-FRMPD2 Antibody

• Catalog number
  5455
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  FRMPD2 Antibody: The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD2 also contains an N-terminal KIND domain and three PDZ domains and is structurally similar to the protein tyrosine phosphatase PTP-BL. FRMPD2 is localized in a polarized fashion in epithelial cells at the basolateral membrane and partially co-localizes with the tight-junction marker protein Zonula-occuldens-1. Suppression of FRMPD2 expression via RNAi in Caco-2 cells results in an impairment of tight junction formation, indicating that FRMPD2 plays a major role in tight junction formation. Other experiments indicate that FRMPD2 is a binding partner to several catenin family members and recruitment of FRMPD2 to cell-cell contacts is dependent on E-cadherin-mediated cell-cell adhesion.
• Gene names
  FRMPD2 Antibody: PDZK4, PDZD5C, PDZK5C, PDZK4, FERM and PDZ domain-containing protein 2, PDZ domain-containing protein 4
• Antibodie s label
  unlabelled serum
• Purity
  FRMPD2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  FRMPD2 antibody was made against a 15 amino acid synthetic peptide from near the amino terminus of human FRMPD2.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  FRMPD2 antibody can be used for detection of FRMPD2 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL.
• Suspention pH azide
  FRMPD2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  FRMPD2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  281604114
• Ncbi nr
  NP_001018081
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  143162
• GENE symbol
  FRMPD2
• Antigene name
  FERM and PDZ domain containing 2
• Source
  Homo sapiens
• Protein nr
  Q68DX3
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FRMPD2  
• Gene symbol
  FRMPD2
• Short name
  anti-FRMPD2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toFRMPD2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:28572
• Gene
  FRMPD2
• Long gene name
  FERM and PDZ domain containing 2
• Synonyms gene
  • PDZD5C
  • PDZK5C
• Synonyms gene name
  • PDZ domain containing 5C
• Synonyms
  • MGC35285
• GenBank acession
  • AK123038
• Locus
  10q11.22
• Discovery year
  2004-04-15
• Entrez gene record
  143162
• RefSeq identity
  • NM_152428
• Classification
  • PDZ domain containing
  • FERM domain containing
• VEGA ID
  OTTHUMG00000018171

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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