Ingenol 3-angelate

• Catalog number
  2593-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  (2Z)-2-Methyl-2-butenoic acid (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester; PEP 005; Ingenol mebutate
• Description
  Ingenol 3-angelate is a specific Protein Kinase C (PKC) activator and anti-cancer agent.  Displays potent antileukemic activity mediated via the d isoform of PKC.
• CAS Number
  75567-37-2
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₂₅H₃₄O₆
• Molecular Weight
  430.53
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~ 1 mg/ml) or ETOH
• Handling
  Protect from light and air
• Tag Line
  A specific PKC activator
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD07784504
• PubChem CID
  6918670
• PubChem CID Link
• SMILES
  CC=C(C)C(=O)OC1C(=CC23C1(C(C(=CC(C2=O)C4C(C4(C)C)CC3C)CO)O)O)C
• InChi
  InChI=1S/C25H34O6/c1-7-12(2)22(29)31-21-13(3)10-24-14(4)8-17-18(23(17,5)6)16(20(24)28)9-15(11-26)19(27)25(21,24)30/h7,9-10,14,16-19,21,26-27,30H,8,11H2,1-6H3/b12-7-/t14-,16+,17-,18+,19-,21+,24+,25+/m1/s1
• InChi Key
  VDJHFHXMUKFKET-WDUFCVPESA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Ingenol   3-angelate  
• Short name
  Ingenol 3-angelate
• Alternative name
  Ingenol 3-angelate

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