HGF, human recombinant
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Catalog number4509-1000
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PricePlease ask
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Size1 mg
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SynonymsScatter Factor (SF), Hepatopoietin (HPTA), HGF, HGFB, F-TCF
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Alternative_namesScatter Factor (SF), Hepatopoietin (HPTA), HGF, HGFB, F-TCF
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DescriptionA growth factor regulating cell growth, cell motility, and morphogenesis
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RecombinantYes
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SourceBaculovirus infected High-5 cells
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Purity by SDS PAGE≥98%
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AssaySDS-PAGE
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Purity≥98%
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Biological activityThe ED₅₀ determined by the scattering activity in the MDCK cell assay is typically at 0.5-1.0 ng/ml.
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Results0.5-1.0 ng/ml
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Molecular Weight78.0 kDa
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Storage Temp-20°C
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ShippingGel pack
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Shelf Life12 months
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AppearanceLyophilized protein
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Physical form descriptionLyophilized from solution containing 50 mM Acetic acid
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Reconstitution InstructionsReconstitute in H₂O to a concentration of 0.5-1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
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Background InformationHuman Hepatocyte Growth Factor (HGF) is also known as Scatter Factor and Hepatopoeitin A. HGF is a potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. Recombinant human HGF is an 80 kDa disulfide-linked heterodimeric protein consisting of the α chain (463 amino acids) and the β chain (234 amino acids).
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolSOS1, HGF, IL6
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Short nameHGF, recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative namehepatocyte growth factor (hepapoietin A; scatter factor), H. sapiens Rec.
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Alternative techniquerec
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Alternative to gene targethepatocyte growth factor (hepapoietin A; scatter factor), DFNB39 and F-TCF and HGFB and HPTA and SF, HGF and IDBG-24150 and ENSG00000019991 and 3082, protein heterodimerization activity, Extracellular, Hgf and IDBG-136449 and ENSMUSG00000028864 and 15234, HGF and IDBG-631194 and ENSBTAG00000017664 and 282879
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Gene info
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Identity
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Gene
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Long gene nameSOS Ras/Rac guanine nucleotide exchange factor 1
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Synonyms gene
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Synonyms gene name
- gingival fibromatosis, hereditary, 1
- son of sevenless homolog 1 (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-10-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Dbl family Rho GEFs
- Pleckstrin homology domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namehepatocyte growth factor
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Synonyms gene
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Synonyms gene name
- deafness, autosomal recessive 39
- hepatocyte growth factor (hepapoietin A; scatter factor)
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Synonyms
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Synonyms name
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Locus
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Discovery year1991-06-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 6
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Synonyms gene
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Synonyms gene name
- interleukin 6 (interferon, beta 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
- Interferons
- Interleukin 6 type cytokine family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data