PAI-1 (NBD P1' mutant) reports cleavage[PAI-1]

Products_type

Protein
Products_gene_name

[PAI-1]
Gene

Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. Elevated PAI-1 is a risk factor for thrombosis and atherosclerosis

Gene target

PAI-1 NBD mutant reports cleavage[PAI-1]
Gene symbol

SERPINE1, SERPINB2, SERBP1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1
Short name

PAI-1 (NBD P1' mutant) reports cleavage[PAI-1]
Alternative name

PAI-1 (NBD P1' mutant) reports cleavage[PAI-1]

Identity

HGNC:8583
Gene

SERPINE1
Long gene name

serpin family E member 1
Synonyms gene
- PLANH1
- PAI1
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Synonyms
- PAI
Synonyms name
- plasminogen activator inhibitor, type I
GenBank acession
- M16006
Locus

7q22.1
Discovery year

1986-01-01
Entrez gene record

5054
Pubmed identfication
- 3097076
- 2891140
- 24172014
RefSeq identity
- NM_000602
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000157107
Locus Specific Databases
- LRG_597

Identity

HGNC:8584
Gene

SERPINB2
Long gene name

serpin family B member 2
Synonyms gene
- PLANH2
- PAI2
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
- serpin peptidase inhibitor, clade B (ovalbumin), member 2
Synonyms
- HsT1201
- PAI-2
Synonyms name
- plasminogen-activator inhibitor
GenBank acession
- Y00630
Locus

18q21.33-q22.1
Discovery year

1989-02-07
Entrez gene record

5055
Pubmed identfication
- 24172014
RefSeq identity
- NM_002575
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000060592

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081