TRPM2 Antibody

• Catalog number
  R31355
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TRPM2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the TRPM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TRPM2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O94759
• Purity
  Antigen affinity
• Description
  Transient receptor potential cation channel subfamily M member 2 is a protein that in humans is encoded by the TRPM2 gene. Using a cosmid/BAC contig, this gene is mapped to chromosome 21q22.3. The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
• Immunogen
  An amino acid sequence from the N-terminus of human TRPM2 (CGYTHEQHLEEATKPH) was used as the immunogen for this TRPM2 antibody.
• Storage
  After reconstitution, the TRPM2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRPM2  
• Gene symbol
  TRPM2-AS, TRPM2
• Short name
  Anti-TRPM2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to TRPM2
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:50758
• Gene
  TRPM2-AS
• Long gene name
  TRPM2 antisense RNA
• Synonyms
  • TRPM2-AS1
• GenBank acession
  • AK057275
• Locus
  21q22.3
• Discovery year
  2014-06-01
• Entrez gene record
  101928607
• Pubmed identfication
  • 18957938
  • 24931166
  • 28678322
• RefSeq identity
  • NR_109964
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000040845

Gene info

• Identity
  HGNC:12339
• Gene
  TRPM2
• Long gene name
  transient receptor potential cation channel subfamily M member 2
• Synonyms gene
  • TRPC7
• Synonyms gene name
  • transient receptor potential cation channel, subfamily M, member 2
• Synonyms
  • KNP3
  • LTRPC2
  • NUDT9L1
  • NUDT9H
  • EREG1
• GenBank acession
  • AB001535
• Locus
  21q22.3
• Discovery year
  1998-03-23
• Entrez gene record
  7226
• Pubmed identfication
  • 9806837
  • 11385575
  • 16382100
• RefSeq identity
  • NM_003307
• Classification
  • Transient receptor potential cation channels
  • Nudix hydrolase family
• VEGA ID
  OTTHUMG00000040840

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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