anti-HDAC5 (phospho Ser498) Antibody

  • Catalog number
    79-192
  • Price
    Please ask
  • Size
    0.1 mg
  • Gene info
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
  • Gene names
    HD5, NY-CO-9, NFKB3, HD5
  • Antibodie s label
    unlabelled serum
  • Purity
    Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Spicific to
    This antibody detects endogenous level of HDAC5 only when phosphorylated at serine498.
  • Antigen
    HDAC5 (Phospho-Ser498) antibody was made against a peptide sequence around phosphorylation site of serine 498 (T-Q-S (p) -S-P) derived from Human HDAC5/7.
  • Immuno application
    Western Blot, immuno-histo-chemistry
  • Antibody advice
    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
  • Suspention pH azide
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Keep at
    Store antibody at -20 grades C for up to one year.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    62750349
  • Ncbi nr
    NP_001015053.1
  • KDa
    124 kDa
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    10014
  • GENE symbol
    HDAC5
  • Antigene name
    histone deacetylase 5
  • Source
    Homo sapiens
  • Protein nr
    Q9UQL6
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    HDAC5   phospho   Ser498  
  • Gene symbol
    HDAC5
  • Short name
    anti-HDAC5 (phospho Ser498) Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toHDAC5 (phosphorilated Ser498) (antibody to-)
  • Alternative technique
    antibodies
  • Alternative to gene target
    histone deacetylase 5, HD5 and NY-CO-9, HDAC5 and IDBG-53295 and ENSG00000108840 and 10014, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac5 and IDBG-212520 and ENSMUSG00000008855 and 15184, HDAC5 and IDBG-640847 and ENSBTAG00000016254 and 504242
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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