SDHC Antibody
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Catalog numberR30937
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenSDHC
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, IHC-P
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Recommended dilutionsWestern blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
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NotesThe stated application concentrations are suggested starting amounts. Titration of the SDHC antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis SDHC antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ99643
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PurityAntigen affinity
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DescriptionThe Succinate dehydrogenase complex, subunit C (SDHC), also called SDH3, gene contains 6 exons. Oostveen et al.(1995) found that in fact it was protein from the bovine SDHC/SDH3 gene (encoding 1 of the 2 integral membrane proteins) that complemented the hamster mutation. The authors localized the human SDH3 gene to the short arm of chromosome one, within 1 to 2 Mb from the centromere. Additionally, the authors stated that Southern analyses of human genomic DNA suggested that there are multiple SDH3 genes or pseudogenes. Elbehti-Green et al.(1998) confirmed the assignment of the SDHC gene to 1q21 by FISH. Baysal et al.(2004) described a family with PGL3 in which an 8,372-bp deletion in the SDHC gene was transmitted both maternally and paternally, without evidence of genomic imprinting.
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ImmunogenAn amino acid sequence from the N-terminus of human Succinate dehydrogenase complex subunit C (KEEMERFWNKNIGSNR) was used as the immunogen for this SDHC antibody.
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StorageAfter reconstitution, the SDHC antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSDHC
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Short nameAnti-SDHC
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to SDHC
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namesuccinate dehydrogenase complex subunit C
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Synonyms gene
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Synonyms gene name
- succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD
- succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-10-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mitochondrial complex II: succinate dehydrogenase subunits
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data