HK2 (Hexokinase II) (Center) Antibody

• Catalog number
  3145-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  HK2 (Hexokinase II)
• Target Alternative Name
  Hexokinase type II, HK II, Muscle form hexokinase
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthetic peptide selected from the 409 - 439 amino acids center region of human HK2.
• Accession
  P52789
• Gene Id
  3099
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.25 mg/ml
• Formulation
  100 µg (0.25 mg/ml) purified rabbit Ig polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Purification
  Affinity purified
• Application
  ELISA, Western blot, Immunohistochemistry
• Positive Control
  Western Blot: A375 cell lysate Immunohistochemistry: Human cancer tissue
• Application And Usages
  The antibody can be used for ELISA (0.25 µg/ml), Western blotting (0.5 – 2.5 µg/ml) and Immunohistochemistry (2.5 – 5.0 µg/ml).
• Description
  In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase activity is involved in the first step in several metabolic pathways. HK3 is bound to the outer mitochondrial membrane. Its hydrophobic N-terminal sequence may be involved in membrane bindng. It is the predominant hexokinase isozyme expressed in insuline-responsive tissues such as skeletal muscle. The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated wiht the N-terminus. Althoμgh found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HK2   Hexokinase   Center  
• Gene symbol
  HK2, HOOK2, HK2-DT, KIF2A, KCNA5
• Short name
  HK2 (Hexokinase II) (Center) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  HK2 (Hexokinase II) (central) (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4923
• Gene
  HK2
• Long gene name
  hexokinase 2
• Locus
  2p12
• Discovery year
  1993-03-11
• Entrez gene record
  3099
• RefSeq identity
  • NM_000189
• VEGA ID
  OTTHUMG00000129972

Gene info

• Identity
  HGNC:19885
• Gene
  HOOK2
• Long gene name
  hook microtubule tethering protein 2
• Synonyms gene name
  • hook homolog 2 (Drosophila)
• Synonyms
  • HK2
• GenBank acession
  • AF044924
• Locus
  19p13.13
• Discovery year
  2003-11-25
• Entrez gene record
  29911
• Pubmed identfication
  • 9927460
• RefSeq identity
  • NM_013312
• Classification
  • FHF complex
• VEGA ID
  OTTHUMG00000180372

Gene info

• Identity
  HGNC:55204
• Gene
  HK2-DT
• Long gene name
  HK2 divergent transcript
• Locus
  2p12
• Discovery year
  2020-08-21
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:6318
• Gene
  KIF2A
• Long gene name
  kinesin family member 2A
• Synonyms gene
  • KIF2
• Synonyms gene name
  • kinesin heavy chain member 2
• Synonyms
  • HK2
• GenBank acession
  • BC031828
• Locus
  5q12.1
• Discovery year
  1997-05-09
• Entrez gene record
  3796
• Pubmed identfication
  • 9177777
• RefSeq identity
  • NM_004520
• Classification
  • Kinesins
• VEGA ID
  OTTHUMG00000097755

Gene info

• Identity
  HGNC:6224
• Gene
  KCNA5
• Long gene name
  potassium voltage-gated channel subfamily A member 5
• Synonyms gene name
  • potassium voltage-gated channel, shaker-related subfamily, member 5
• Synonyms
  • Kv1.5
  • HK2
  • HPCN1
• GenBank acession
  • M83254
• Locus
  12p13.32
• Discovery year
  1991-08-13
• Entrez gene record
  3741
• Pubmed identfication
  • 16382104
• RefSeq identity
  • NM_002234
• Classification
  • Potassium voltage-gated channels
• VEGA ID
  OTTHUMG00000168232

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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